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    fgf7 fibroblast growth factor 7 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 496833, updated on 4-Nov-2024

    Summary

    Official Symbol
    fgf7provided by Xenbase
    Official Full Name
    fibroblast growth factor 7provided by Xenbase
    Primary source
    Xenbase:XB-GENE-488183
    See related
    Ensembl:ENSXETG00000037937 AllianceGenome:Xenbase:XB-GENE-488183
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    kgf; hbgf-7
    Summary
    Predicted to enable growth factor activity and type 2 fibroblast growth factor receptor binding activity. Predicted to be involved in several processes, including fibroblast growth factor receptor signaling pathway; positive regulation of MAPK cascade; and positive regulation of epithelial cell proliferation. Predicted to be active in cytoplasm and extracellular space. Is expressed in anatomical system; ectoderm; mesenchyme; and pharyngeal arch. Orthologous to human FGF7 (fibroblast growth factor 7). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See fgf7 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 3 NC_030679.2 (104281317..104315989)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 3 NC_030679.1 (94340424..94374773)

    Chromosome 3 - NC_030679.2Genomic Context describing neighboring genes Neighboring gene COP9 signalosome subunit 2 Neighboring gene galactokinase 2 Neighboring gene family with sequence similarity 227 member B Neighboring gene NAD(P) transhydrogenase, mitochondrial Neighboring gene DTW domain containing 1 Neighboring gene ATPase, class I, type 8B, member 4

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables growth factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables growth factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables type 2 fibroblast growth factor receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in fibroblast growth factor receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in lung development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in neurogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of MAPK cascade IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of epithelial cell proliferation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    fibroblast growth factor 7
    Names
    fibroblast growth factor 7 (keratinocyte growth factor)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001011366.1NP_001011366.1  fibroblast growth factor 7

      See identical proteins and their annotated locations for NP_001011366.1

      Status: PROVISIONAL

      Source sequence(s)
      BC088532
      UniProtKB/TrEMBL
      F7BT02, Q5M7N7
      Related
      ENSXETP00000079053.1, ENSXETT00000067019.2
      Conserved Domains (1) summary
      pfam00167
      Location:65189
      FGF; Fibroblast growth factor

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030679.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      104281317..104315989
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_012958944.3XP_012814398.1  fibroblast growth factor 7 isoform X1

      See identical proteins and their annotated locations for XP_012814398.1

      UniProtKB/TrEMBL
      F7BT02, Q5M7N7
      Conserved Domains (1) summary
      pfam00167
      Location:65189
      FGF; Fibroblast growth factor