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    PLXNA4 plexin A4 [ Canis lupus familiaris (dog) ]

    Gene ID: 482251, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PLXNA4provided by VGNC
    Official Full Name
    plexin A4provided by VGNC
    Primary source
    VGNC:VGNC:44721
    See related
    Ensembl:ENSCAFG00845015377
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See PLXNA4 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    36
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 14 NC_051818.1 (4419335..4847251)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 14 NC_006596.4 (4344388..4770614)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 14 NC_049235.1 (4510104..4938016)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 14 NC_049274.1 (4622751..5050482)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 14 NC_049755.1 (4368126..4795816)

    Chromosome 14 - NC_051818.1Genomic Context describing neighboring genes Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 3 Neighboring gene 60S ribosomal protein L15-like Neighboring gene uncharacterized LOC119867158 Neighboring gene uncharacterized LOC111098723 Neighboring gene uncharacterized LOC111098658 Neighboring gene uncharacterized LOC119867214

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables semaphorin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of axonogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell shape IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in semaphorin-plexin signaling pathway involved in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of semaphorin receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    plexin-A4; LOW QUALITY PROTEIN: plexin-A4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051818.1 Reference ROS_Cfam_1.0

      Range
      4419335..4847251
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038686096.1 → XP_038542024.1  plexin-A4 isoform X1

      UniProtKB/TrEMBL
      A0A8P0N4I9
      Conserved Domains (10) summary
      cd11274
      Location:38 → 510
      Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
      smart00423
      Location:509 → 547
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00603
      Location:1141 → 1221
      IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
      cd01179
      Location:954 → 1037
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:857 → 952
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01181
      Location:1039 → 1139
      IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:803 → 855
      PSI; Plexin repeat
      pfam08337
      Location:1310 → 1870
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      pfam17960
      Location:563 → 653
      TIG_plexin; TIG domain
      pfam18020
      Location:707 → 801
      TIG_2; TIG domain found in plexin

    2. XM_038686095.1 → XP_038542023.1  plexin-A4 isoform X1

      UniProtKB/TrEMBL
      A0A8P0N4I9
      Conserved Domains (10) summary
      cd11274
      Location:38 → 510
      Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
      smart00423
      Location:509 → 547
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00603
      Location:1141 → 1221
      IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
      cd01179
      Location:954 → 1037
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:857 → 952
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01181
      Location:1039 → 1139
      IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:803 → 855
      PSI; Plexin repeat
      pfam08337
      Location:1310 → 1870
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      pfam17960
      Location:563 → 653
      TIG_plexin; TIG domain
      pfam18020
      Location:707 → 801
      TIG_2; TIG domain found in plexin

    3. XM_038686098.1 → XP_038542026.1  plexin-A4 isoform X2

      UniProtKB/TrEMBL
      A0A8I3NX73, A0A8P0N4I9
      Related
      ENSCAFP00845021596.1, ENSCAFT00845027447.1
      Conserved Domains (10) summary
      cd11274
      Location:38 → 510
      Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
      smart00423
      Location:509 → 547
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00603
      Location:1141 → 1221
      IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
      cd01179
      Location:954 → 1037
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:857 → 952
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01181
      Location:1039 → 1139
      IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:803 → 855
      PSI; Plexin repeat
      pfam08337
      Location:1310 → 1863
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      pfam17960
      Location:563 → 653
      TIG_plexin; TIG domain
      pfam18020
      Location:707 → 801
      TIG_2; TIG domain found in plexin

    4. XM_038686100.1 → XP_038542028.1  plexin-A4 isoform X4

      UniProtKB/TrEMBL
      A0A8C0QDJ5
      Conserved Domains (1) summary
      cl15693
      Location:38 → 457
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    5. XM_038686099.1 → XP_038542027.1  plexin-A4 isoform X3

      Conserved Domains (1) summary
      cl15693
      Location:38 → 469
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    6. XM_038686097.1 → XP_038542025.1  plexin-A4 isoform X1

      UniProtKB/TrEMBL
      A0A8P0N4I9
      Conserved Domains (10) summary
      cd11274
      Location:38 → 510
      Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
      smart00423
      Location:509 → 547
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00603
      Location:1141 → 1221
      IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
      cd01179
      Location:954 → 1037
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:857 → 952
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01181
      Location:1039 → 1139
      IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:803 → 855
      PSI; Plexin repeat
      pfam08337
      Location:1310 → 1870
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      pfam17960
      Location:563 → 653
      TIG_plexin; TIG domain
      pfam18020
      Location:707 → 801
      TIG_2; TIG domain found in plexin

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049274.1 Alternate UMICH_Zoey_3.1

      Range
      4622751..5050482
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038494184.1 → XP_038350112.1  plexin-A4 isoform X1

      Conserved Domains (10) summary
      cd11274
      Location:38 → 510
      Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
      smart00423
      Location:509 → 547
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00603
      Location:1141 → 1221
      IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
      cd01179
      Location:954 → 1037
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:857 → 952
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01181
      Location:1039 → 1139
      IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:803 → 855
      PSI; Plexin repeat
      pfam08337
      Location:1310 → 1870
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      pfam17960
      Location:563 → 653
      TIG_plexin; TIG domain
      pfam18020
      Location:707 → 801
      TIG_2; TIG domain found in plexin

    2. XM_038494183.1 → XP_038350111.1  plexin-A4 isoform X1

      Conserved Domains (10) summary
      cd11274
      Location:38 → 510
      Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
      smart00423
      Location:509 → 547
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00603
      Location:1141 → 1221
      IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
      cd01179
      Location:954 → 1037
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:857 → 952
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01181
      Location:1039 → 1139
      IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:803 → 855
      PSI; Plexin repeat
      pfam08337
      Location:1310 → 1870
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      pfam17960
      Location:563 → 653
      TIG_plexin; TIG domain
      pfam18020
      Location:707 → 801
      TIG_2; TIG domain found in plexin

    3. XM_038494186.1 → XP_038350114.1  plexin-A4 isoform X2

    4. XM_038494188.1 → XP_038350116.1  plexin-A4 isoform X4

      Conserved Domains (1) summary
      cl15693
      Location:38 → 457
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    5. XM_038494187.1 → XP_038350115.1  plexin-A4 isoform X3

      Conserved Domains (1) summary
      cl15693
      Location:38 → 469
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    6. XM_038494185.1 → XP_038350113.1  plexin-A4 isoform X1

      Conserved Domains (10) summary
      cd11274
      Location:38 → 510
      Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
      smart00423
      Location:509 → 547
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00603
      Location:1141 → 1221
      IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
      cd01179
      Location:954 → 1037
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:857 → 952
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01181
      Location:1039 → 1139
      IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:803 → 855
      PSI; Plexin repeat
      pfam08337
      Location:1310 → 1870
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      pfam17960
      Location:563 → 653
      TIG_plexin; TIG domain
      pfam18020
      Location:707 → 801
      TIG_2; TIG domain found in plexin

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049755.1 Alternate UNSW_CanFamBas_1.0

      Range
      4368126..4795816
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038620410.1 → XP_038476338.1  plexin-A4 isoform X1

      Conserved Domains (10) summary
      cd11274
      Location:38 → 510
      Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
      smart00423
      Location:509 → 547
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00603
      Location:1141 → 1221
      IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
      cd01179
      Location:954 → 1037
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:857 → 952
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01181
      Location:1039 → 1139
      IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:803 → 855
      PSI; Plexin repeat
      pfam08337
      Location:1310 → 1870
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      pfam17960
      Location:563 → 653
      TIG_plexin; TIG domain
      pfam18020
      Location:707 → 801
      TIG_2; TIG domain found in plexin

    2. XM_038620409.1 → XP_038476337.1  plexin-A4 isoform X1

      Conserved Domains (10) summary
      cd11274
      Location:38 → 510
      Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
      smart00423
      Location:509 → 547
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00603
      Location:1141 → 1221
      IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
      cd01179
      Location:954 → 1037
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:857 → 952
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01181
      Location:1039 → 1139
      IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:803 → 855
      PSI; Plexin repeat
      pfam08337
      Location:1310 → 1870
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      pfam17960
      Location:563 → 653
      TIG_plexin; TIG domain
      pfam18020
      Location:707 → 801
      TIG_2; TIG domain found in plexin

    3. XM_038620412.1 → XP_038476340.1  plexin-A4 isoform X2

    4. XM_038620414.1 → XP_038476342.1  plexin-A4 isoform X4

      Conserved Domains (1) summary
      cl15693
      Location:38 → 457
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    5. XM_038620413.1 → XP_038476341.1  plexin-A4 isoform X3

      Conserved Domains (1) summary
      cl15693
      Location:38 → 469
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    6. XM_038620411.1 → XP_038476339.1  plexin-A4 isoform X1

      Conserved Domains (10) summary
      cd11274
      Location:38 → 510
      Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
      smart00423
      Location:509 → 547
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00603
      Location:1141 → 1221
      IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
      cd01179
      Location:954 → 1037
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:857 → 952
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01181
      Location:1039 → 1139
      IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:803 → 855
      PSI; Plexin repeat
      pfam08337
      Location:1310 → 1870
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      pfam17960
      Location:563 → 653
      TIG_plexin; TIG domain
      pfam18020
      Location:707 → 801
      TIG_2; TIG domain found in plexin

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049235.1 Alternate UU_Cfam_GSD_1.0

      Range
      4510104..4938016
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038556478.1 → XP_038412406.1  plexin-A4 isoform X1

      UniProtKB/TrEMBL
      A0A8P0N4I9
      Conserved Domains (10) summary
      cd11274
      Location:38 → 510
      Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
      smart00423
      Location:509 → 547
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00603
      Location:1141 → 1221
      IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
      cd01179
      Location:954 → 1037
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:857 → 952
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01181
      Location:1039 → 1139
      IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:803 → 855
      PSI; Plexin repeat
      pfam08337
      Location:1310 → 1870
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      pfam17960
      Location:563 → 653
      TIG_plexin; TIG domain
      pfam18020
      Location:707 → 801
      TIG_2; TIG domain found in plexin

    2. XM_038556477.1 → XP_038412405.1  plexin-A4 isoform X1

      UniProtKB/TrEMBL
      A0A8P0N4I9
      Conserved Domains (10) summary
      cd11274
      Location:38 → 510
      Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
      smart00423
      Location:509 → 547
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00603
      Location:1141 → 1221
      IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
      cd01179
      Location:954 → 1037
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:857 → 952
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01181
      Location:1039 → 1139
      IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:803 → 855
      PSI; Plexin repeat
      pfam08337
      Location:1310 → 1870
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      pfam17960
      Location:563 → 653
      TIG_plexin; TIG domain
      pfam18020
      Location:707 → 801
      TIG_2; TIG domain found in plexin

    3. XM_038556480.1 → XP_038412408.1  plexin-A4 isoform X2

      UniProtKB/TrEMBL
      A0A8P0N4I9

    4. XM_038556482.1 → XP_038412410.1  plexin-A4 isoform X4

      UniProtKB/TrEMBL
      A0A8C0QDJ5
      Conserved Domains (1) summary
      cl15693
      Location:38 → 457
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    5. XM_038556481.1 → XP_038412409.1  plexin-A4 isoform X3

      Conserved Domains (1) summary
      cl15693
      Location:38 → 469
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    6. XM_038556479.1 → XP_038412407.1  plexin-A4 isoform X1

      UniProtKB/TrEMBL
      A0A8P0N4I9
      Conserved Domains (10) summary
      cd11274
      Location:38 → 510
      Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
      smart00423
      Location:509 → 547
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00603
      Location:1141 → 1221
      IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
      cd01179
      Location:954 → 1037
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:857 → 952
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01181
      Location:1039 → 1139
      IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:803 → 855
      PSI; Plexin repeat
      pfam08337
      Location:1310 → 1870
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      pfam17960
      Location:563 → 653
      TIG_plexin; TIG domain
      pfam18020
      Location:707 → 801
      TIG_2; TIG domain found in plexin

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006596.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      4344388..4770614
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_539370.7 → XP_539370.3  LOW QUALITY PROTEIN: plexin-A4 isoform X2

      UniProtKB/TrEMBL
      A0A8P0N4I9
      Conserved Domains (10) summary
      cd11274
      Location:38 → 510
      Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
      smart00423
      Location:509 → 547
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00603
      Location:1141 → 1221
      IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
      cd01179
      Location:954 → 1037
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:857 → 952
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01181
      Location:1039 → 1139
      IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:803 → 855
      PSI; Plexin repeat
      pfam08337
      Location:1310 → 1863
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      pfam17960
      Location:563 → 653
      TIG_plexin; TIG domain
      pfam18020
      Location:707 → 801
      TIG_2; TIG domain found in plexin
    Nucleotide Protein
    Heading Accession and Version

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