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    SLC12A2 solute carrier family 12 member 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 481490, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SLC12A2provided by VGNC
    Official Full Name
    solute carrier family 12 member 2provided by VGNC
    Primary source
    VGNC:VGNC:46219
    See related
    Ensembl:ENSCAFG00845011539
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See SLC12A2 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 11 NC_051815.1 (17881289..17994035)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 11 NC_006593.4 (15939385..16051806)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 11 NC_049232.1 (17054476..17167223)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 11 NC_049271.1 (16604869..16717534)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 11 NC_049752.1 (16450079..16562728)

    Chromosome 11 - NC_051815.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111098011 Neighboring gene uncharacterized LOC119874032 Neighboring gene uncharacterized LOC119873881 Neighboring gene ferritin heavy chain-like Neighboring gene uncharacterized LOC111097970 Neighboring gene fibrillin 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ammonium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sodium:potassium:chloride symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell volume homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chloride ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chloride transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in potassium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in potassium ion import across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sodium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in sodium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    solute carrier family 12 member 2; LOW QUALITY PROTEIN: solute carrier family 12 member 2
    Names
    solute carrier family 12 (sodium/potassium/chloride transporters), member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051815.1 Reference ROS_Cfam_1.0

      Range
      17881289..17994035
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038681414.1 → XP_038537342.1  solute carrier family 12 member 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0P7G9, A0A8I3NAD4
      Related
      ENSCAFP00845016909.1, ENSCAFT00845021516.1
      Conserved Domains (1) summary
      TIGR00930
      Location:235 → 1231
      2a30; K-Cl cotransporter

    2. XM_038681415.1 → XP_038537343.1  solute carrier family 12 member 2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0P7P4, A0A8I3NAK7
      Related
      ENSCAFP00845017007.1, ENSCAFT00845021637.1
      Conserved Domains (1) summary
      TIGR00930
      Location:235 → 1215
      2a30; K-Cl cotransporter

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049271.1 Alternate UMICH_Zoey_3.1

      Range
      16604869..16717534
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038489987.1 → XP_038345915.1  LOW QUALITY PROTEIN: solute carrier family 12 member 2 isoform X1

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049752.1 Alternate UNSW_CanFamBas_1.0

      Range
      16450079..16562728
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038615920.1 → XP_038471848.1  solute carrier family 12 member 2 isoform X1

    2. XM_038615921.1 → XP_038471849.1  solute carrier family 12 member 2 isoform X2

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049232.1 Alternate UU_Cfam_GSD_1.0

      Range
      17054476..17167223
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038552056.1 → XP_038407984.1  solute carrier family 12 member 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0P7G9

    2. XM_038552057.1 → XP_038407985.1  solute carrier family 12 member 2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0P7P4

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006593.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      15939385..16051806
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_538611.7 → XP_538611.7  solute carrier family 12 member 2 isoform X1

      UniProtKB/TrEMBL
      A0A8C0P7G9, A0A8C0QPV6, A0A8P0S6N4
      Conserved Domains (1) summary
      TIGR00930
      Location:222 → 1218
      2a30; K-Cl cotransporter

    2. XM_038669176.1 → XP_038525104.1  solute carrier family 12 member 2 isoform X2

      UniProtKB/TrEMBL
      A0A8C0P7P4, A0A8C0QGM9, A0A8P0T7Z5
      Conserved Domains (1) summary
      TIGR00930
      Location:222 → 1202
      2a30; K-Cl cotransporter
    Nucleotide Protein
    Heading Accession and Version

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