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    RUFY1 RUN and FYVE domain containing 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 481454, updated on 17-Aug-2024

    Summary

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    Official Symbol
    RUFY1provided by VGNC
    Official Full Name
    RUN and FYVE domain containing 1provided by VGNC
    Primary source
    VGNC:VGNC:45803
    See related
    Ensembl:ENSCAFG00845008457
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See RUFY1 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 11 NC_051815.1 (2036939..2101959, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 11 NC_006593.4 (2185367..2250065, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 11 NC_049232.1 (2327760..2392746, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 11 NC_049271.1 (2008407..2073373, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 11 NC_049752.1 (2087009..2151921, complement)

    Chromosome 11 - NC_051815.1Genomic Context describing neighboring genes Neighboring gene chibby family member 3 Neighboring gene heterogeneous nuclear ribonucleoprotein H1 Neighboring gene uncharacterized LOC111097914 Neighboring gene small nucleolar RNA SNORA54 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 2 Neighboring gene uncharacterized LOC111097978

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RUN and FYVE domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051815.1 Reference ROS_Cfam_1.0

      Range
      2036939..2101959 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038681135.1 → XP_038537063.1  RUN and FYVE domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8I3N3X3, A0A8I3NKP5
      Related
      ENSCAFP00845011691.1, ENSCAFT00845015066.1
      Conserved Domains (3) summary
      TIGR02169
      Location:371 → 636
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      cd15758
      Location:626 → 696
      FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
      pfam02759
      Location:139 → 260
      RUN; RUN domain

    2. XM_038681140.1 → XP_038537068.1  RUN and FYVE domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0JQH7, A0A8C0S243, A0A8C0YRE9, A0A8I3RW37
      Related
      ENSCAFP00845011547.1, ENSCAFT00845014896.1
      Conserved Domains (3) summary
      TIGR02169
      Location:271 → 536
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      cd15758
      Location:526 → 596
      FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
      pfam02759
      Location:39 → 160
      RUN; RUN domain

    3. XM_038681139.1 → XP_038537067.1  RUN and FYVE domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0JQH7, A0A8C0S243, A0A8C0YRE9, A0A8I3RW37
      Conserved Domains (3) summary
      TIGR02169
      Location:271 → 536
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      cd15758
      Location:526 → 596
      FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
      pfam02759
      Location:39 → 160
      RUN; RUN domain

    4. XM_038681138.1 → XP_038537066.1  RUN and FYVE domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0JQH7, A0A8C0S243, A0A8C0YRE9, A0A8I3RW37
      Conserved Domains (3) summary
      TIGR02169
      Location:271 → 536
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      cd15758
      Location:526 → 596
      FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
      pfam02759
      Location:39 → 160
      RUN; RUN domain

    5. XM_038681136.1 → XP_038537064.1  RUN and FYVE domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0RDY7
      Conserved Domains (2) summary
      TIGR02169
      Location:371 → 629
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam02759
      Location:139 → 260
      RUN; RUN domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049271.1 Alternate UMICH_Zoey_3.1

      Range
      2008407..2073373 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038489743.1 → XP_038345671.1  RUN and FYVE domain-containing protein 1 isoform X3

      Conserved Domains (3) summary
      TIGR02169
      Location:271 → 536
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      cd15758
      Location:526 → 596
      FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
      pfam02759
      Location:39 → 160
      RUN; RUN domain

    2. XM_038489742.1 → XP_038345670.1  RUN and FYVE domain-containing protein 1 isoform X3

      Conserved Domains (3) summary
      TIGR02169
      Location:271 → 536
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      cd15758
      Location:526 → 596
      FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
      pfam02759
      Location:39 → 160
      RUN; RUN domain

    3. XM_038489741.1 → XP_038345669.1  RUN and FYVE domain-containing protein 1 isoform X3

      Conserved Domains (3) summary
      TIGR02169
      Location:271 → 536
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      cd15758
      Location:526 → 596
      FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
      pfam02759
      Location:39 → 160
      RUN; RUN domain

    4. XM_038489740.1 → XP_038345668.1  RUN and FYVE domain-containing protein 1 isoform X3

      Conserved Domains (3) summary
      TIGR02169
      Location:271 → 536
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      cd15758
      Location:526 → 596
      FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
      pfam02759
      Location:39 → 160
      RUN; RUN domain

    5. XM_038489744.1 → XP_038345672.1  RUN and FYVE domain-containing protein 1 isoform X4

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049752.1 Alternate UNSW_CanFamBas_1.0

      Range
      2087009..2151921 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038615647.1 → XP_038471575.1  RUN and FYVE domain-containing protein 1 isoform X1

      Conserved Domains (3) summary
      TIGR02169
      Location:371 → 636
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      cd15758
      Location:626 → 696
      FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
      pfam02759
      Location:139 → 260
      RUN; RUN domain

    2. XM_038615651.1 → XP_038471579.1  RUN and FYVE domain-containing protein 1 isoform X3

      Conserved Domains (3) summary
      TIGR02169
      Location:271 → 536
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      cd15758
      Location:526 → 596
      FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
      pfam02759
      Location:39 → 160
      RUN; RUN domain

    3. XM_038615650.1 → XP_038471578.1  RUN and FYVE domain-containing protein 1 isoform X3

      Conserved Domains (3) summary
      TIGR02169
      Location:271 → 536
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      cd15758
      Location:526 → 596
      FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
      pfam02759
      Location:39 → 160
      RUN; RUN domain

    4. XM_038615649.1 → XP_038471577.1  RUN and FYVE domain-containing protein 1 isoform X3

      Conserved Domains (3) summary
      TIGR02169
      Location:271 → 536
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      cd15758
      Location:526 → 596
      FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
      pfam02759
      Location:39 → 160
      RUN; RUN domain

    5. XM_038615648.1 → XP_038471576.1  RUN and FYVE domain-containing protein 1 isoform X2

      Conserved Domains (2) summary
      TIGR02169
      Location:371 → 629
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam02759
      Location:139 → 260
      RUN; RUN domain

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049232.1 Alternate UU_Cfam_GSD_1.0

      Range
      2327760..2392746 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038551760.1 → XP_038407688.1  RUN and FYVE domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8I3N3X3, A0A8I3NKP5
      Conserved Domains (3) summary
      TIGR02169
      Location:371 → 636
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      cd15758
      Location:626 → 696
      FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
      pfam02759
      Location:139 → 260
      RUN; RUN domain

    2. XM_038551765.1 → XP_038407693.1  RUN and FYVE domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0JQH7, A0A8C0S243, A0A8C0YRE9, A0A8I3RW37
      Conserved Domains (3) summary
      TIGR02169
      Location:271 → 536
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      cd15758
      Location:526 → 596
      FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
      pfam02759
      Location:39 → 160
      RUN; RUN domain

    3. XM_038551764.1 → XP_038407692.1  RUN and FYVE domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0JQH7, A0A8C0S243, A0A8C0YRE9, A0A8I3RW37
      Conserved Domains (3) summary
      TIGR02169
      Location:271 → 536
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      cd15758
      Location:526 → 596
      FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
      pfam02759
      Location:39 → 160
      RUN; RUN domain

    4. XM_038551762.1 → XP_038407690.1  RUN and FYVE domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8C0JQH7, A0A8C0S243, A0A8C0YRE9, A0A8I3RW37
      Conserved Domains (3) summary
      TIGR02169
      Location:271 → 536
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      cd15758
      Location:526 → 596
      FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
      pfam02759
      Location:39 → 160
      RUN; RUN domain

    5. XM_038551761.1 → XP_038407689.1  RUN and FYVE domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0RDY7
      Conserved Domains (2) summary
      TIGR02169
      Location:371 → 629
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam02759
      Location:139 → 260
      RUN; RUN domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006593.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      2185367..2250065 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_843736.6 → XP_848829.4  RUN and FYVE domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8P0N3M8, A0A8P0SSY7
      Conserved Domains (3) summary
      TIGR02169
      Location:371 → 636
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      cd15758
      Location:626 → 696
      FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
      pfam02759
      Location:139 → 260
      RUN; RUN domain

    2. XM_005626305.4 → XP_005626362.1  RUN and FYVE domain-containing protein 1 isoform X3

      See identical proteins and their annotated locations for XP_005626362.1

      UniProtKB/TrEMBL
      A0A8C0JQH7, A0A8C0S243, A0A8C0YRE9, A0A8I3RW37
      Conserved Domains (3) summary
      TIGR02169
      Location:271 → 536
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      cd15758
      Location:526 → 596
      FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
      pfam02759
      Location:39 → 160
      RUN; RUN domain

    3. XM_005626304.4 → XP_005626361.1  RUN and FYVE domain-containing protein 1 isoform X3

      See identical proteins and their annotated locations for XP_005626361.1

      UniProtKB/TrEMBL
      A0A8C0JQH7, A0A8C0S243, A0A8C0YRE9, A0A8I3RW37
      Conserved Domains (3) summary
      TIGR02169
      Location:271 → 536
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      cd15758
      Location:526 → 596
      FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
      pfam02759
      Location:39 → 160
      RUN; RUN domain

    4. XM_005626306.4 → XP_005626363.1  RUN and FYVE domain-containing protein 1 isoform X3

      See identical proteins and their annotated locations for XP_005626363.1

      UniProtKB/TrEMBL
      A0A8C0JQH7, A0A8C0S243, A0A8C0YRE9, A0A8I3RW37
      Conserved Domains (3) summary
      TIGR02169
      Location:271 → 536
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      cd15758
      Location:526 → 596
      FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
      pfam02759
      Location:39 → 160
      RUN; RUN domain

    5. XM_005626303.4 → XP_005626360.2  RUN and FYVE domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8C0RDY7
      Conserved Domains (2) summary
      TIGR02169
      Location:371 → 629
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam02759
      Location:139 → 260
      RUN; RUN domain
    Nucleotide Protein
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