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    ARSG arylsulfatase G [ Canis lupus familiaris (dog) ]

    Gene ID: 480460, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ARSGprovided by VGNC
    Official Full Name
    arylsulfatase Gprovided by VGNC
    Primary source
    VGNC:VGNC:51920
    See related
    Ensembl:ENSCAFG00845029010
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See ARSG in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (16669828..16777722)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (15941642..16006895)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (11811933..11877177, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (15656480..15721673)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (11811569..11876963, complement)

    Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111097331 Neighboring gene G protein subunit alpha 13 Neighboring gene archaelysin family metallopeptidase 2 Neighboring gene solute carrier family 16 member 6 Neighboring gene WD repeat domain, phosphoinositide interacting 1 Neighboring gene protein kinase cAMP-dependent type I regulatory subunit alpha

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A canine Arylsulfatase G (ARSG) mutation leading to a sulfatase deficiency is associated with neuronal ceroid lipofuscinosis. Abitbol M, et al. Proc Natl Acad Sci U S A, 2010 Aug 17. PMID 20679209, Free PMC Article
    2. Sulfatases and sulfatase modifying factors: an exclusive and promiscuous relationship. Sardiello M, et al. Hum Mol Genet, 2005 Nov 1. PMID 16174644
    3. Genome sequence, comparative analysis and haplotype structure of the domestic dog. Lindblad-Toh K, et al. Nature, 2005 Dec 8. PMID 16341006
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data provide a functional confirmation that the arylsulfatase G variant might be the NCL-causing mutation.
      Title: A canine Arylsulfatase G (ARSG) mutation leading to a sulfatase deficiency is associated with neuronal ceroid lipofuscinosis.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables arylsulfatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    arylsulfatase G
    Names
    ASG
    N-sulfoglucosamine-3-sulfatase
    NP_001041563.1
    XP_038530919.1
    XP_038530920.1
    XP_038530921.1
    XP_038530922.1
    XP_038530923.1
    XP_038530924.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001048098.1 → NP_001041563.1  arylsulfatase G precursor

      See identical proteins and their annotated locations for NP_001041563.1

      Status: PROVISIONAL

      Source sequence(s)
      BN000758
      UniProtKB/Swiss-Prot
      Q32KH9
      UniProtKB/TrEMBL
      A0A8C0R9M9, A0A8P0SFY1
      Conserved Domains (2) summary
      COG3119
      Location:35 → 488
      AslA; Arylsulfatase A or related enzyme [Inorganic ion transport and metabolism]
      cd16161
      Location:35 → 469
      ARSG; arylsulfatase G

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051813.1 Reference ROS_Cfam_1.0

      Range
      16669828..16777722
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038674994.1 → XP_038530922.1  arylsulfatase G isoform X1

      UniProtKB/TrEMBL
      A0A8C0R9M9
      Conserved Domains (1) summary
      cd16161
      Location:35 → 500
      ARSG; arylsulfatase G

    2. XM_038674991.1 → XP_038530919.1  arylsulfatase G isoform X1

      UniProtKB/TrEMBL
      A0A8C0R9M9
      Conserved Domains (1) summary
      cd16161
      Location:35 → 500
      ARSG; arylsulfatase G

    3. XM_038674996.1 → XP_038530924.1  arylsulfatase G isoform X3

      UniProtKB/TrEMBL
      A0A8C0R7E9, A0A8C0R9M9, A0A8I3Q0D0
      Related
      ENSCAFP00845040293.1, ENSCAFT00845051360.1
      Conserved Domains (1) summary
      cd16161
      Location:35 → 469
      ARSG; arylsulfatase G

    4. XM_038674995.1 → XP_038530923.1  arylsulfatase G isoform X2

      UniProtKB/TrEMBL
      A0A8C0R9M9
      Conserved Domains (1) summary
      cd16161
      Location:35 → 499
      ARSG; arylsulfatase G

    5. XM_038674992.1 → XP_038530920.1  arylsulfatase G isoform X1

      UniProtKB/TrEMBL
      A0A8C0R9M9
      Conserved Domains (1) summary
      cd16161
      Location:35 → 500
      ARSG; arylsulfatase G

    6. XM_038674993.1 → XP_038530921.1  arylsulfatase G isoform X1

      UniProtKB/TrEMBL
      A0A8C0R9M9
      Conserved Domains (1) summary
      cd16161
      Location:35 → 500
      ARSG; arylsulfatase G

    RNA

    1. XR_005431681.1 RNA Sequence

    2. XR_005431680.1 RNA Sequence

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049269.1 Alternate UMICH_Zoey_3.1

      Range
      15656480..15721673
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

      Range
      11811569..11876963 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

      Range
      11811933..11877177 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      15941642..16006895
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q32KH9.1 GenPept UniProtKB/Swiss-Prot:Q32KH9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials