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    ALCAM activated leukocyte cell adhesion molecule [ Canis lupus familiaris (dog) ]

    Gene ID: 478550, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ALCAMprovided by VGNC
    Official Full Name
    activated leukocyte cell adhesion moleculeprovided by VGNC
    Primary source
    VGNC:VGNC:37779
    See related
    Ensembl:ENSCAFG00845022356
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See ALCAM in Genome Data Viewer
    Location:
    chromosome: 33
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 33 NC_051837.1 (11141772..11353405)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 33 NC_006615.4 (11088414..11300048)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 33 NC_049254.1 (11486320..11697980)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 33 NC_049293.1 (11011197..11222028)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 33 NC_049774.1 (11078031..11289490)

    Chromosome 33 - NC_051837.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111093724 Neighboring gene uncharacterized LOC111093782 Neighboring gene vacuolar protein sorting-associated protein 29-like Neighboring gene Cbl proto-oncogene B Neighboring gene uncharacterized LOC102156767 Neighboring gene protein S100-A10-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mesenchymal stem cell surface antigen SB-10 corresponds to activated leukocyte cell adhesion molecule and is involved in osteogenic differentiation. Bruder SP, et al. J Bone Miner Res, 1998 Apr. PMID 9556065
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    CD166 antigen
    Names
    SB-10 antigen

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001313804.2 → NP_001300733.1  CD166 antigen precursor

      Status: PROVISIONAL

      Source sequence(s)
      JAAUVH010000367
      UniProtKB/TrEMBL
      A0A8C0K6B4, A0A8C0T4H7, A0A8I3PIH3
      Related
      ENSCAFP00845030928.1, ENSCAFT00845039467.1
      Conserved Domains (5) summary
      smart00406
      Location:38 → 113
      IGv; Immunoglobulin V-Type
      smart00410
      Location:339 → 393
      IG_like; Immunoglobulin like
      pfam08205
      Location:137 → 231
      C2-set_2; CD80-like C2-set immunoglobulin domain
      pfam13927
      Location:250 → 313
      Ig_3; Immunoglobulin domain
      cd00096
      Location:137 → 141
      Ig; Ig strand A' [structural motif]

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051837.1 Reference ROS_Cfam_1.0

      Range
      11141772..11353405
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038444577.1 → XP_038300505.1  CD166 antigen isoform X1

      UniProtKB/TrEMBL
      A0A8C0K6B4, A0A8C0T4H7, A0A8I3PIH3
      Conserved Domains (5) summary
      smart00406
      Location:38 → 113
      IGv; Immunoglobulin V-Type
      smart00410
      Location:339 → 393
      IG_like; Immunoglobulin like
      pfam08205
      Location:137 → 231
      C2-set_2; CD80-like C2-set immunoglobulin domain
      pfam13927
      Location:250 → 313
      Ig_3; Immunoglobulin domain
      cd00096
      Location:137 → 141
      Ig; Ig strand A' [structural motif]

    2. XM_038444578.1 → XP_038300506.1  CD166 antigen isoform X2

      UniProtKB/TrEMBL
      A0A8C0K4D0, A0A8C0T1S2, A0A8I3S5N7
      Related
      ENSCAFP00845031030.1, ENSCAFT00845039610.1
      Conserved Domains (5) summary
      smart00406
      Location:38 → 113
      IGv; Immunoglobulin V-Type
      smart00410
      Location:339 → 393
      IG_like; Immunoglobulin like
      pfam08205
      Location:137 → 231
      C2-set_2; CD80-like C2-set immunoglobulin domain
      pfam13927
      Location:250 → 313
      Ig_3; Immunoglobulin domain
      cd00096
      Location:137 → 141
      Ig; Ig strand A' [structural motif]

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049293.1 Alternate UMICH_Zoey_3.1

      Range
      11011197..11222028
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049774.1 Alternate UNSW_CanFamBas_1.0

      Range
      11078031..11289490
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049254.1 Alternate UU_Cfam_GSD_1.0

      Range
      11486320..11697980
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006615.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      11088414..11300048
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O46634.1 GenPept UniProtKB/Swiss-Prot:O46634

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials