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    SMC6 structural maintenance of chromosomes 6 [ Canis lupus familiaris (dog) ]

    Gene ID: 475675, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SMC6provided by VGNC
    Official Full Name
    structural maintenance of chromosomes 6provided by VGNC
    Primary source
    VGNC:VGNC:46547
    See related
    Ensembl:ENSCAFG00845016537
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See SMC6 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 17 NC_051821.1 (13269396..13337856, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 17 NC_006599.4 (13085159..13153159, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 17 NC_049238.1 (13165157..13233234, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 17 NC_049277.1 (13127707..13196134, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 17 NC_049758.1 (13138902..13207328, complement)

    Chromosome 17 - NC_051821.1Genomic Context describing neighboring genes Neighboring gene RAD51 associated protein 2 Neighboring gene visinin like 1 Neighboring gene microRNA mir-8845 Neighboring gene dnaJ homolog subfamily A member 1-like Neighboring gene GEN1 Holliday junction 5' flap endonuclease Neighboring gene mesogenin 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables damaged DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables single-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in double-strand break repair via homologous recombination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Smc5-Smc6 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in site of double-strand break IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    structural maintenance of chromosomes protein 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051821.1 Reference ROS_Cfam_1.0

      Range
      13269396..13337856 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038690761.1 → XP_038546689.1  structural maintenance of chromosomes protein 6

      UniProtKB/TrEMBL
      A0A8I3P052, A0A8I3P8X8
      Related
      ENSCAFP00845023096.1, ENSCAFT00845029385.1
      Conserved Domains (1) summary
      COG1196
      Location:53 → 1074
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    2. XM_038690762.1 → XP_038546690.1  structural maintenance of chromosomes protein 6

      UniProtKB/TrEMBL
      A0A8I3P052, A0A8I3P8X8
      Related
      ENSCAFP00845023330.1, ENSCAFT00845029704.1
      Conserved Domains (1) summary
      COG1196
      Location:53 → 1074
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    RNA

    1. XR_005439899.1 RNA Sequence

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049277.1 Alternate UMICH_Zoey_3.1

      Range
      13127707..13196134 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038498270.1 → XP_038354198.1  structural maintenance of chromosomes protein 6

      Conserved Domains (1) summary
      COG1196
      Location:53 → 1074
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    2. XM_038498271.1 → XP_038354199.1  structural maintenance of chromosomes protein 6

      Conserved Domains (1) summary
      COG1196
      Location:53 → 1074
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    RNA

    1. XR_005338354.1 RNA Sequence

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049758.1 Alternate UNSW_CanFamBas_1.0

      Range
      13138902..13207328 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038624850.1 → XP_038480778.1  structural maintenance of chromosomes protein 6

      Conserved Domains (1) summary
      COG1196
      Location:53 → 1074
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    2. XM_038624851.1 → XP_038480779.1  structural maintenance of chromosomes protein 6

      Conserved Domains (1) summary
      COG1196
      Location:53 → 1074
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

    RNA

    1. XR_005406253.1 RNA Sequence

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049238.1 Alternate UU_Cfam_GSD_1.0

      Range
      13165157..13233234 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038560825.1 → XP_038416753.1  structural maintenance of chromosomes protein 6

      UniProtKB/TrEMBL
      A0A8P0P228, A0A8P0S9J7

    2. XM_038560826.1 → XP_038416754.1  structural maintenance of chromosomes protein 6

      UniProtKB/TrEMBL
      A0A8P0P228, A0A8P0S9J7

    RNA

    1. XR_005372147.1 RNA Sequence

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006599.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      13085159..13153159 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_532882.7 → XP_532882.3  structural maintenance of chromosomes protein 6

      See identical proteins and their annotated locations for XP_532882.3

      UniProtKB/TrEMBL
      A0A8P0P228, A0A8P0S9J7
      Conserved Domains (1) summary
      cl25732
      Location:54 → 1075
      SMC_N; RecF/RecN/SMC N terminal domain

    2. XM_022404471.2 → XP_022260179.1  structural maintenance of chromosomes protein 6

      UniProtKB/TrEMBL
      A0A8P0P228, A0A8P0S9J7
      Conserved Domains (1) summary
      cl25732
      Location:54 → 1075
      SMC_N; RecF/RecN/SMC N terminal domain

    RNA

    1. XR_005311071.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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