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    MAP2K6 mitogen-activated protein kinase kinase 6 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 468310, updated on 10-Oct-2024

    Summary

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    Official Symbol
    MAP2K6provided by VGNC
    Official Full Name
    mitogen-activated protein kinase kinase 6provided by VGNC
    Primary source
    VGNC:VGNC:9365
    Locus tag
    CK820_G0038067
    See related
    Ensembl:ENSPTRG00000009588
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    See MAP2K6 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 19 NC_072417.2 (82390176..82530657)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 17 NC_072415.1 (80574656..80715106)

    Chromosome 19 - NC_072417.2Genomic Context describing neighboring genes Neighboring gene small nuclear ribonucleoprotein G-like Neighboring gene ATP binding cassette subfamily A member 5 Neighboring gene small nucleolar RNA SNORA40 Neighboring gene uncharacterized LOC107969310 Neighboring gene uncharacterized LOC100614898 Neighboring gene uncharacterized LOC134808919

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables MAP kinase kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    dual specificity mitogen-activated protein kinase kinase 6
    XP_009431432.1
    XP_063655986.1
    XP_523699.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072417.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      82390176..82530657
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_523699.9 → XP_523699.2  dual specificity mitogen-activated protein kinase kinase 6 isoform X1

      See identical proteins and their annotated locations for XP_523699.2

      UniProtKB/TrEMBL
      A0A2I3RB56, A0A2J8KKV1, A0A6D2WAD6, H2QZW5
      Related
      ENSPTRP00000039686.3
      Conserved Domains (1) summary
      cd06617
      Location:51 → 333
      PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

    2. XM_009433157.5 → XP_009431432.1  dual specificity mitogen-activated protein kinase kinase 6 isoform X2

      See identical proteins and their annotated locations for XP_009431432.1

      UniProtKB/TrEMBL
      A0A2I3RB56, A0A2I3T777, A0A2J8KKV2, A0A6D2XQ66
      Conserved Domains (1) summary
      cd06617
      Location:1 → 277
      PKc_MKK3_6; Catalytic domain of the dual-specificity Protein Kinases, Mitogen-activated protein Kinase Kinases 3 and 6

    3. XM_063799916.1 → XP_063655986.1  dual specificity mitogen-activated protein kinase kinase 6 isoform X2

      UniProtKB/TrEMBL
      A0A2I3T777, A0A2J8KKV2, A0A6D2XQ66
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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