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    USP46 ubiquitin specific peptidase 46 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 461329, updated on 10-Oct-2024

    Summary

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    Official Symbol
    USP46provided by VGNC
    Official Full Name
    ubiquitin specific peptidase 46provided by VGNC
    Primary source
    VGNC:VGNC:12937
    Locus tag
    CK820_G0003173
    See related
    Ensembl:ENSPTRG00000043855
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    See USP46 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 3 NC_072401.2 (77209146..77272545)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 4 NC_072402.1 (77209173..77272519)

    Chromosome 3 - NC_072401.2Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA26 Neighboring gene endogenous retrovirus group MER34 member 1, envelope Neighboring gene uncharacterized LOC129143742 Neighboring gene small nucleolar RNA SNORA26 Neighboring gene differentiation antagonizing non-protein coding RNA Neighboring gene uncharacterized LOC134809888 Neighboring gene uncharacterized LOC107974322

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ubiquitin carboxyl-terminal hydrolase 46
    XP_016807234.1
    XP_054539111.1
    XP_517296.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072401.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      77209146..77272545
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_517296.9 → XP_517296.2  ubiquitin carboxyl-terminal hydrolase 46 isoform X1

      See identical proteins and their annotated locations for XP_517296.2

      UniProtKB/TrEMBL
      A0A2I3TKE4, A0A2J8PEJ5, A0A6D2XTP9, H2QPG6
      Related
      ENSPTRP00000075637.1
      Conserved Domains (1) summary
      cd02663
      Location:36 → 363
      Peptidase_C19G; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...

    2. XM_054683136.2 → XP_054539111.1  ubiquitin carboxyl-terminal hydrolase 46 isoform X3

      UniProtKB/TrEMBL
      A0A2I3S5E5, A0A2J8PEJ8, A0A6D2X484

    3. XM_016951745.4 → XP_016807234.1  ubiquitin carboxyl-terminal hydrolase 46 isoform X2

      UniProtKB/TrEMBL
      A0A2I3SMB8, A0A2I3TKE4, A0A2J8PEK0, A0A6D2Y2I0
      Related
      ENSPTRP00000078115.1
      Conserved Domains (1) summary
      cd02663
      Location:29 → 356
      Peptidase_C19G; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    Nucleotide Protein
    Heading Accession and Version

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