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    lef anthrax toxin lethal factor [ Bacillus anthracis str. 'Ames Ancestor' ]

    Gene ID: 45025515, updated on 6-Jun-2024

    Summary

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    Gene symbol
    lef
    Gene description
    anthrax toxin lethal factor
    Locus tag
    GBAA_RS29135
    Gene type
    protein coding
    Organism
    Bacillus anthracis str. 'Ames Ancestor' (strain: Ames Ancestor; A2084)
    Lineage
    Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus; Bacillus cereus group
    Old locus tag
    GBAA_pXO1_0172
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    Genomic context

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    Location:
    plasmid: pXO1
    Sequence:
    NC_007322.2 (149357..151786, complement)

    NC_007322.2Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene pseudo Neighboring gene pseudo Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_007322.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Effect of pH and denaturants on the fold and metal status of anthrax lethal factor. Lo SY, et al. Arch Biochem Biophys, 2020 Oct 15. PMID 32828796
    2. Anthrax lethal and edema toxins in anthrax pathogenesis. Liu S, et al. Trends Microbiol, 2014 Jun. PMID 24684968, Free PMC Article
    3. The complete genome sequence of Bacillus anthracis Ames "Ancestor". Ravel J, et al. J Bacteriol, 2009 Jan. PMID 18952800, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Effect of pH and denaturants on the fold and metal status of anthrax lethal factor.
      Title: Effect of pH and denaturants on the fold and metal status of anthrax lethal factor.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General protein information

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    Preferred Names
    anthrax toxin lethal factor

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_007322.2 Reference assembly

      Range
      149357..151786 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_001022097.1 anthrax toxin lethal factor [Bacillus anthracis]

      See identical proteins and their annotated locations for WP_001022097.1

      UniProtKB/Swiss-Prot
      P15917, Q8KYJ6, Q933F6
      UniProtKB/TrEMBL
      I3XID9, Q52NH3
      Conserved Domains (2) summary
      pfam07737
      Location:69 → 286
      ATLF; Anthrax toxin lethal factor, N- and C-terminal domain
      pfam09156
      Location:298 → 583
      Anthrax-tox_M; Anthrax toxin lethal factor, middle domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut