styxl1 serine/threonine/tyrosine interacting-like 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: styxl1provided by ZNC
Official Full Name: serine/threonine/tyrosine interacting-like 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040912-45
See related: Ensembl:ENSDARG00000026338 AllianceGenome:ZFIN:ZDB-GENE-040912-45
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:101812
Summary: Predicted to enable protein phosphatase binding activity; protein phosphatase inhibitor activity; and pseudophosphatase activity. Predicted to be involved in negative regulation of stress granule assembly and positive regulation of intrinsic apoptotic signaling pathway. Predicted to act upstream of or within protein dephosphorylation. Predicted to be active in mitochondrion. Orthologous to human STYXL1 (serine/threonine/tyrosine interacting like 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 10

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	10	NC_007121.7 (35257651..35262368)
105	previous assembly	GRCz10 (GCF_000002035.5)	10	NC_007121.6 (35313816..35318508)

Chromosome 10 - NC_007121.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables protein phosphatase binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein phosphatase inhibitor activity	IBA Inferred from Biological aspect of Ancestor more info
enables pseudophosphatase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within dephosphorylation	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of stress granule assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of intrinsic apoptotic signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein dephosphorylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: serine/threonine/tyrosine-interacting-like protein 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001004619.1 → NP_001004619.1 serine/threonine/tyrosine-interacting-like protein 1

See identical proteins and their annotated locations for NP_001004619.1

Status: PROVISIONAL

Source sequence(s)

BC081407

UniProtKB/TrEMBL

Q66IC4

Related

ENSDARP00000037865.4, ENSDART00000028940.5

Conserved Domains (2) summary

cl00125
Location:33 → 121

RHOD; Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins ...

cl21483
Location:142 → 279

PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...