prmt6.S protein arginine methyltransferase 6 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: prmt6.S
Official Full Name: protein arginine methyltransferase 6 S homeolog
Primary source: Xenbase:XB-GENE-6254002
Locus tag: XELAEV_18014152mg
See related: EnsemblRapid:ENSXLAG00005028195 AllianceGenome:Xenbase:XB-GENE-6254002
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: prmt6
Summary: Predicted to enable histone binding activity and protein-arginine N-methyltransferase activity. Predicted to act upstream of or within negative regulation of DNA-templated transcription and negative regulation of ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. Orthologous to human PRMT6 (protein arginine methyltransferase 6). [provided by Alliance of Genome Resources, Nov 2024]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 2S

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	2S	NC_054374.1 (4055730..4057043, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	2S	NC_030727.1 (4063875..4065188, complement)

Chromosome 2S - NC_054374.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables histone H2AR3 methyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables histone H3R2 methyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables histone H4R3 methyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables histone binding	ISS Inferred from Sequence or Structural Similarity more info
enables histone methyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables protein-arginine N-methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables protein-arginine N-methyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables protein-arginine omega-N asymmetric methyltransferase activity	IEA Inferred from Electronic Annotation more info
enables protein-arginine omega-N asymmetric methyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables protein-arginine omega-N monomethyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA repair	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within chromatin organization	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within methylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within negative regulation of DNA-templated transcription	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within negative regulation of ubiquitin-dependent protein catabolic process	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within peptidyl-arginine methylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

Go to the top of the page Help

Preferred Names: protein arginine N-methyltransferase 6

Names: Histone-arginine N-methyltransferase PRMT6

NP_001087520.1

EC 2.1.1.319

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001094051.1 → NP_001087520.1 protein arginine N-methyltransferase 6

See identical proteins and their annotated locations for NP_001087520.1

Status: PROVISIONAL

Source sequence(s)

BC080055

UniProtKB/Swiss-Prot

Q68EZ3

UniProtKB/TrEMBL

A0A974HUQ4

Related

ENSXLAP00005083861.1, ENSXLAT00005085500.1

Conserved Domains (2) summary

pfam05185
Location:34 → 282

PRMT5; PRMT5 arginine-N-methyltransferase

pfam12847
Location:53 → 156

Methyltransf_18; Methyltransferase domain