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    crym.S crystallin mu S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 447114, updated on 4-Nov-2024

    Summary

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    Official Symbol
    crym.S
    Official Full Name
    crystallin mu S homeolog
    Primary source
    Xenbase:XB-GENE-17334370
    Locus tag
    XELAEV_18047637mg
    See related
    EnsemblRapid:ENSXLAG00005007760 AllianceGenome:Xenbase:XB-GENE-17334370
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Summary
    Predicted to enable thiomorpholine-carboxylate dehydrogenase activity and thyroid hormone binding activity. Predicted to act upstream of or within thyroid hormone metabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 40. Orthologous to human CRYM (crystallin mu). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See crym.S in Genome Data Viewer
    Location:
    chromosome: 9_10S
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10S NC_054388.1 (97281553..97299460)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10S NC_030741.1 (90633673..90651584)

    Chromosome 9_10S - NC_054388.1Genomic Context describing neighboring genes Neighboring gene modulator of smoothened S homeolog Neighboring gene ubiquinol-cytochrome c reductase core protein 2 S homeolog Neighboring gene ankyrin repeat and sterile alpha motif domain containing 4B S homeolog Neighboring gene uncharacterized LOC108702310

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC85331

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables thiomorpholine-carboxylate dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables thyroid hormone binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within thyroid hormone metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    crystallin mu S homeolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001093823.2 → NP_001087292.1  crystallin mu S homeolog

      See identical proteins and their annotated locations for NP_001087292.1

      Status: PROVISIONAL

      Source sequence(s)
      BC078518
      UniProtKB/TrEMBL
      A0A974C0I6, A0A974H1L6, Q66KY1
      Related
      ENSXLAP00005022199.1, ENSXLAT00005022890.1
      Conserved Domains (2) summary
      pfam02423
      Location:13 → 312
      OCD_Mu_crystall; Ornithine cyclodeaminase/mu-crystallin family
      cl21454
      Location:13 → 312
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      97281553..97299460
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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    Research Materials