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    LOC4344397 L-ascorbate peroxidase 2, cytosolic-like [ Oryza sativa Japonica Group (Japanese rice) ]

    Gene ID: 4344397, updated on 17-Jul-2024

    Summary

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    Gene symbol
    LOC4344397
    Gene description
    L-ascorbate peroxidase 2, cytosolic-like
    Locus tag
    OSNPB_070694700
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Oryza sativa Japonica Group
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa
    Also known as
    APX2; APXb; SS622; OsAPx2; OsAPx02; OsJ_25704
    Expression
    Ubiquitous expression in flowers (RPKM 239.4), flower buds (RPKM 180.3) and 6 other tissues See more
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    Genomic context

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    See LOC4344397 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_06 current ASM3414082v1 (GCF_034140825.1) 7 NC_089041.1 (29818072..29820707, complement)
    102 previous assembly IRGSP-1.0 (GCF_001433935.1) 7 NC_029262.1 (29584030..29586347, complement)

    Chromosome 7 - NC_089041.1Genomic Context describing neighboring genes Neighboring gene PWWP domain-containing protein 5 Neighboring gene arogenate dehydratase/prephenate dehydratase 2, chloroplastic Neighboring gene protein RETARDED ROOT GROWTH, mitochondrial Neighboring gene uncharacterized LOC136357469

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome profiling of various organs at different developmental stages in rice Transcriptome profiling of various organs at different developmental stages in rice
    • Description: Transcriptom profiling in flower buds, flowers, flag leaves and roots sampled before flowering and after flowering, milk grains and mature seeds
    • BioProject: PRJNA243371
    • Publication: PMID 26387578
    • Analysis date: Fri Dec 15 20:02:59 2017

    Bibliography

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    Related articles in PubMed

    1. Functional switching of ascorbate peroxidase 2 of rice (OsAPX2) between peroxidase and molecular chaperone. Hong SH, et al. Sci Rep, 2018 Jun 15. PMID 29907832, Free PMC Article
    2. Cytosolic APX2 is a pleiotropic protein involved in H(2)O(2) homeostasis, chloroplast protection, plant architecture and fertility maintenance. Wu B, et al. Plant Cell Rep, 2018 Jun. PMID 29549445
    3. Enhanced chilling tolerance at the booting stage in rice by transgenic overexpression of the ascorbate peroxidase gene, OsAPXa. Sato Y, et al. Plant Cell Rep, 2011 Mar. PMID 21203887
    4. Rice ascorbate peroxidase gene family encodes functionally diverse isoforms localized in different subcellular compartments. Teixeira FK, et al. Planta, 2006 Jul. PMID 16397796
    5. Purification and characterization of two ascorbate peroxidases of rice (Oryza sativa L.) expressed in Escherichia coli. Lu Z, et al. Biotechnol Lett, 2005 Jan. PMID 15685422

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The different functions of OsAPX2 correlate strongly with its structural conformation. The high-molecular-weight (HMW) complexes had chaperone activity, whereas the low-molecular-weight (LMW) forms displayed predominantly APX activity. The APX activity was effectively inhibited by sodium azide, which is an inhibitor of haem-containing enzymes, but this did not affect the protein's activity as a chaperone.
      Title: Functional switching of ascorbate peroxidase 2 of rice (OsAPX2) between peroxidase and molecular chaperone.
    2. cytosolic APX2 is a pleiotropic protein and an important regulator in reactive oxygen species homeostasis, chloroplast protection, carbohydrate metabolism as well as plant architecture and fertility maintenance.
      Title: Cytosolic APX2 is a pleiotropic protein involved in H(2)O(2) homeostasis, chloroplast protection, plant architecture and fertility maintenance.
    3. Higher APX activity enhances H2O2-scavenging capacity and protects spikelets from lipid peroxidation, thereby increasing spikelet fertility under cold stress.
      Title: Enhanced chilling tolerance at the booting stage in rice by transgenic overexpression of the ascorbate peroxidase gene, OsAPXa.
    4. Exogenously applied H2O2 enhanced the activity and expression of ascorbaate peroxidase.
      Title: Expression of ascorbate peroxidase and glutathione reductase in roots of rice seedlings in response to NaCl and H2O2.
    5. These findings reveal the functional diversity of the rice APx genes and suggest complementation and coordination of the antioxidant defenses in different cellular compartments during development and abiotic stress.
      Title: Rice ascorbate peroxidase gene family encodes functionally diverse isoforms localized in different subcellular compartments.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables peroxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in hydrogen peroxide catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to reactive oxygen species IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    L-ascorbate peroxidase 2, cytosolic
    Names
    LOC_Os07g49400
    P0627E10.14
    ascobate peroxidase
    ascorbate peroxidase
    NP_001390213.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001403284.1 → NP_001390213.1  L-ascorbate peroxidase 2, cytosolic

      Status: VALIDATED

      Source sequence(s)
      AK068430, CI248327, CI759458, GQ848056
      UniProtKB/Swiss-Prot
      Q0D3B8, Q40735, Q9FE01
      UniProtKB/TrEMBL
      A0A345YV75, B8B6B6

    RefSeqs of Annotated Genomes: GCF_034140825.1-RS_2024_06

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM3414082v1 Primary Assembly

    Genomic

    1. NC_089041.1 Reference ASM3414082v1 Primary Assembly

      Range
      29818072..29820707 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FE01.1 GenPept UniProtKB/Swiss-Prot:Q9FE01

    Gene LinkOut

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    Research Materials