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    frrs1.L ferric-chelate reductase 1 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 432203, updated on 4-Nov-2024

    Summary

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    Official Symbol
    frrs1.L
    Official Full Name
    ferric-chelate reductase 1 L homeolog
    Primary source
    Xenbase:XB-GENE-989223
    Locus tag
    XELAEV_18023293mg
    See related
    EnsemblRapid:ENSXLAG00005026729 AllianceGenome:Xenbase:XB-GENE-989223
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    fcr1; frrs1
    Summary
    Predicted to enable metal ion binding activity and oxidoreductase activity, acting on metal ions. Predicted to act upstream of or within intracellular iron ion homeostasis. Predicted to be located in membrane. Orthologous to human FRRS1 (ferric chelate reductase 1). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See frrs1.L in Genome Data Viewer
    Location:
    chromosome: 4L
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (97337638..97368869)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (92072969..92104187)

    Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene sterol O-acyltransferase 1 L homeolog Neighboring gene uncharacterized LOC108713660 Neighboring gene palmdelphin L homeolog Neighboring gene solute carrier family 44 member 3 L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC80281

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on metal ions IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within intracellular iron ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative ferric-chelate reductase 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001091659.1 → NP_001085128.1  putative ferric-chelate reductase 1 precursor

      See identical proteins and their annotated locations for NP_001085128.1

      Status: PROVISIONAL

      Source sequence(s)
      BC072175
      UniProtKB/Swiss-Prot
      Q6INU7
      UniProtKB/TrEMBL
      A0A974HNY5
      Related
      ENSXLAP00005079812.1, ENSXLAT00005081405.1
      Conserved Domains (3) summary
      cd08760
      Location:319 → 532
      Cyt_b561_FRRS1_like; Eukaryotic cytochrome b(561), including the FRRS1 gene product
      cd09628
      Location:191 → 347
      DOMON_SDR_2_like; DOMON domain of stromal cell-derived receptor 2 (ferric chelate reductase 1) and related proteins
      pfam02014
      Location:31 → 154
      Reeler; Reeler domain

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      97337638..97368869
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018256658.2 → XP_018112147.1  putative ferric-chelate reductase 1 isoform X1

      UniProtKB/TrEMBL
      A0A1L8GMP7, A0A974HNY5, A0A974HPG3
      Related
      ENSXLAP00005079484.1, ENSXLAT00005081074.1

    2. XM_018256657.2 → XP_018112146.1  putative ferric-chelate reductase 1 isoform X1

      UniProtKB/TrEMBL
      A0A1L8GMP7, A0A974HNY5, A0A974HPG3
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6INU7.1 GenPept UniProtKB/Swiss-Prot:Q6INU7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.