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    FAN1 FANCD2/FANCI-associated nuclease 1 [ Gallus gallus (chicken) ]

    Gene ID: 415383, updated on 17-Aug-2024

    Summary

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    Symbol
    FAN1provided by CGNC
    Full Name
    FANCD2/FANCI-associated nuclease 1provided by CGNC
    Primary source
    CGNC:2854
    See related
    Ensembl:ENSGALG00010024762
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    MTMR15
    Orthologs
    human mouse all
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    Genomic context

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    See FAN1 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 10 NC_052541.1 (5790770..5807160, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 10 NC_052582.1 (5665198..5681596, complement)

    Chromosome 10 - NC_052541.1Genomic Context describing neighboring genes Neighboring gene transient receptor potential cation channel subfamily M member 1 Neighboring gene uncharacterized LOC121111663 Neighboring gene microRNA 204-2 Neighboring gene myotubularin related protein 10 Neighboring gene M-phase phosphoprotein 10 Neighboring gene amyloid beta precursor protein binding family A member 2 Neighboring gene methylmalonyl-CoA epimerase Neighboring gene family with sequence similarity 189 member A1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. FANCD2-Associated Nuclease 1 Partially Compensates for the Lack of Exonuclease 1 in Mismatch Repair. Kratz K, et al. Mol Cell Biol, 2021 Aug 24. PMID 34228493, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. FANCD2-Associated Nuclease 1 Partially Compensates for the Lack of Exonuclease 1 in Mismatch Repair.
      Title: FANCD2-Associated Nuclease 1 Partially Compensates for the Lack of Exonuclease 1 in Mismatch Repair.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 5'-3' exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables 5'-flap endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables flap-structured DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in interstrand cross-link repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    fanconi-associated nuclease 1
    Names
    FANCD2 and FANCI associated nuclease 1
    myotubularin related protein 15
    XP_004943817.1
    XP_004943818.1
    XP_040536590.1
    XP_040536591.1
    XP_040536592.1
    XP_040536593.1
    XP_040536596.1
    XP_040536597.1
    XP_040562786.1
    XP_040562787.1
    XP_413768.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052541.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      5790770..5807160 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004943761.5 → XP_004943818.1  fanconi-associated nuclease 1 isoform X1

      See identical proteins and their annotated locations for XP_004943818.1

      Conserved Domains (2) summary
      smart00734
      Location:57 → 78
      ZnF_Rad18; Rad18-like CCHC zinc finger
      smart00990
      Location:915 → 1027
      VRR_NUC; This model contains proteins with the VRR-NUC domain

    2. XM_004943760.5 → XP_004943817.1  fanconi-associated nuclease 1 isoform X1

      See identical proteins and their annotated locations for XP_004943817.1

      Conserved Domains (2) summary
      smart00734
      Location:57 → 78
      ZnF_Rad18; Rad18-like CCHC zinc finger
      smart00990
      Location:915 → 1027
      VRR_NUC; This model contains proteins with the VRR-NUC domain

    3. XM_413768.7 → XP_413768.2  fanconi-associated nuclease 1 isoform X2

      UniProtKB/TrEMBL
      A0A3Q2UDF6
      Related
      ENSGALP00010037206.1, ENSGALT00010060447.1
      Conserved Domains (2) summary
      cl02765
      Location:57 → 78
      zf-WRNIP1_ubi; Werner helicase-interacting protein 1 ubiquitin-binding domain
      cd22326
      Location:385 → 1034
      FAN1-like; repair nuclease FAN1

    4. XM_040706853.2 → XP_040562787.1  fanconi-associated nuclease 1 isoform X4

      Conserved Domains (1) summary
      cl02765
      Location:57 → 78
      zf-WRNIP1_ubi; Werner helicase-interacting protein 1 ubiquitin-binding domain

    5. XM_040706852.2 → XP_040562786.1  fanconi-associated nuclease 1 isoform X3

      Conserved Domains (1) summary
      cl02765
      Location:57 → 78
      zf-WRNIP1_ubi; Werner helicase-interacting protein 1 ubiquitin-binding domain

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052582.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      5665198..5681596 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040680658.2 → XP_040536592.1  fanconi-associated nuclease 1 isoform X1

      Conserved Domains (2) summary
      smart00734
      Location:57 → 78
      ZnF_Rad18; Rad18-like CCHC zinc finger
      smart00990
      Location:918 → 1030
      VRR_NUC; This model contains proteins with the VRR-NUC domain

    2. XM_040680657.2 → XP_040536591.1  fanconi-associated nuclease 1 isoform X1

      Conserved Domains (2) summary
      smart00734
      Location:57 → 78
      ZnF_Rad18; Rad18-like CCHC zinc finger
      smart00990
      Location:918 → 1030
      VRR_NUC; This model contains proteins with the VRR-NUC domain

    3. XM_040680659.2 → XP_040536593.1  fanconi-associated nuclease 1 isoform X2

      Conserved Domains (2) summary
      smart00734
      Location:57 → 78
      ZnF_Rad18; Rad18-like CCHC zinc finger
      smart00990
      Location:916 → 1028
      VRR_NUC; This model contains proteins with the VRR-NUC domain

    4. XM_040680656.2 → XP_040536590.1  fanconi-associated nuclease 1 isoform X1

      Conserved Domains (2) summary
      smart00734
      Location:57 → 78
      ZnF_Rad18; Rad18-like CCHC zinc finger
      smart00990
      Location:918 → 1030
      VRR_NUC; This model contains proteins with the VRR-NUC domain

    5. XM_040680663.2 → XP_040536597.1  fanconi-associated nuclease 1 isoform X4

      Conserved Domains (1) summary
      smart00734
      Location:57 → 78
      ZnF_Rad18; Rad18-like CCHC zinc finger

    6. XM_040680662.2 → XP_040536596.1  fanconi-associated nuclease 1 isoform X3

      Conserved Domains (1) summary
      smart00734
      Location:57 → 78
      ZnF_Rad18; Rad18-like CCHC zinc finger
    Nucleotide Protein Strain
    Heading Accession and Version

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