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    CG31522 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40567, updated on 28-Oct-2024

    Summary

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    Official Symbol
    CG31522provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051522
    Locus tag
    Dmel_CG31522
    See related
    AllianceGenome:FB:FBgn0051522
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0118547.381; BcDNA:GH22993; BcDNA:LD10305; CG9798; Dmel\CG31522
    Summary
    Predicted to enable fatty acid elongase activity. Predicted to be involved in fatty acid biosynthetic process and sphingolipid biosynthetic process. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including adult head; anterior endoderm; embryonic dorsal epidermis; embryonic ventral epidermis; and embryonic/larval midgut primordium. Orthologous to human ELOVL1 (ELOVL fatty acid elongase 1) and ELOVL7 (ELOVL fatty acid elongase 7). [provided by Alliance of Genome Resources, Oct 2024]
    Orthologs
    all
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    Genomic context

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    See CG31522 in Genome Data Viewer
    Location:
    82B1-82B2; 3-47.1 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (4441415..4462883, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (267137..288605, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44134 Neighboring gene uncharacterized protein Neighboring gene Lipoyl(octanoyl) transferase 2 Neighboring gene antisense RNA:CR43629 Neighboring gene uncharacterized protein Neighboring gene sterile affecting ciliogenesis

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A computation using mutually exclusive processing is sufficient to identify specific Hedgehog signaling components. Spratt SJ. Front Genet, 2013. PMID 24391661, Free PMC Article
    2. Differential activation of JAK-STAT signaling reveals functional compartmentalization in Drosophila blood progenitors. Rodrigues D, et al. Elife, 2021 Feb 17. PMID 33594977, Free PMC Article
    3. Reverse and forward engineering of Drosophila corneal nanocoatings. Kryuchkov M, et al. Nature, 2020 Sep. PMID 32939070
    4. Sex Differences in Drosophila Somatic Gene Expression: Variation and Regulation by doublesex. Arbeitman MN, et al. G3 (Bethesda), 2016 Jul 7. PMID 27172187, Free PMC Article
    5. A role for very-long-chain fatty acids in furrow ingression during cytokinesis in Drosophila spermatocytes. Szafer-Glusman E, et al. Curr Biol, 2008 Sep 23. PMID 18804373, Free PMC Article

    See all (45) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: c4459690-4459654 mobile_element_type = transposon:INE-1{}3809

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables fatty acid elongase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables fatty acid elongase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables fatty acid elongase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fatty acid elongation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in fatty acid elongation, monounsaturated fatty acid IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in fatty acid elongation, polyunsaturated fatty acid IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in fatty acid elongation, saturated fatty acid IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sphingolipid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in very long-chain fatty acid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG31522-PA
    CG31522-PB
    CG31522-PD
    CG31522-PF
    CG31522-PG
    CG31522-PH
    CG31522-PI
    NP_001246905.2
    NP_001246906.1
    NP_001246907.1
    NP_001262254.1
    NP_730841.2
    NP_730842.2
    NP_730843.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      4441415..4462883 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001259977.1 → NP_001246906.1  uncharacterized protein Dmel_CG31522, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246906.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3PFF2, Q8IPL8
      Conserved Domains (1) summary
      pfam01151
      Location:27 → 266
      ELO; GNS1/SUR4 family

    2. NM_001275325.1 → NP_001262254.1  uncharacterized protein Dmel_CG31522, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262254.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KF65
      Conserved Domains (1) summary
      pfam01151
      Location:27 → 293
      ELO; GNS1/SUR4 family

    3. NM_169002.4 → NP_730842.2  uncharacterized protein Dmel_CG31522, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730842.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3PFF2, Q8IPL8
      Related
      FBpp0078581
      Conserved Domains (1) summary
      pfam01151
      Location:27 → 266
      ELO; GNS1/SUR4 family

    4. NM_001259978.1 → NP_001246907.1  uncharacterized protein Dmel_CG31522, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246907.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3PFF2, Q9VN29
      Conserved Domains (1) summary
      pfam01151
      Location:27 → 265
      ELO; GNS1/SUR4 family

    5. NM_169001.4 → NP_730841.2  uncharacterized protein Dmel_CG31522, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730841.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3PFF2, Q8IPL8
      Related
      FBpp0078579
      Conserved Domains (1) summary
      pfam01151
      Location:27 → 266
      ELO; GNS1/SUR4 family

    6. NM_001259976.2 → NP_001246905.2  uncharacterized protein Dmel_CG31522, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246905.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3PFF2, Q9VN29
      Conserved Domains (1) summary
      pfam01151
      Location:27 → 265
      ELO; GNS1/SUR4 family

    7. NM_169003.4 → NP_730843.2  uncharacterized protein Dmel_CG31522, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730843.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3PFF2, Q9VN29
      Related
      FBpp0078582
      Conserved Domains (1) summary
      pfam01151
      Location:27 → 265
      ELO; GNS1/SUR4 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KF65 A0A0B4KF65
    Q8IPL8 Q8IPL8
    Q8T0D0 Q8T0D0
    Q9VN29 Q9VN29

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