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    ANXA1 annexin A1 [ Gallus gallus (chicken) ]

    Gene ID: 404271, updated on 10-Oct-2024

    Summary

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    Official Symbol
    ANXA1provided by CGNC
    Official Full Name
    annexin A1provided by CGNC
    Primary source
    CGNC:11272
    See related
    Ensembl:ENSGALG00010014114
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    p35; Anx1
    Orthologs
    human mouse all
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    Genomic context

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    See ANXA1 in Genome Data Viewer
    Location:
    chromosome: Z
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (36635449..36653095)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (36635449..36653095)

    Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene probable DNA double-strand break repair Rad50 ATPase-like Neighboring gene uncharacterized LOC112530673 Neighboring gene uncharacterized LOC121108464 Neighboring gene uncharacterized LOC121108519

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Annexins as cell-type-specific markers in the developing chicken chorionallantoic membrane. Matschke K, et al. Cell Tissue Res, 2006 Mar. PMID 16344946
    2. The hinge region of chicken annexin I contains no site for tyrosine phosphorylation. Sidis Y, et al. FEBS Lett, 1993 Aug 30. PMID 8365470
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cadherin binding involved in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium-dependent phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phospholipase A2 inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA duplex unwinding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in alpha-beta T cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in arachidonate secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to glucocorticoid stimulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to hydrogen peroxide IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to vascular endothelial growth factor stimulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in endocrine pancreas development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in gliogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in granulocyte chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in hepatocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in insulin secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in keratinocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in myoblast migration involved in skeletal muscle regeneration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of T-helper 2 cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of phospholipase A2 activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neutrophil clearance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of G1/S transition of mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of T cell proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of T-helper 1 cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cell migration involved in sprouting angiogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of interleukin-2 production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of neutrophil apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of prostaglandin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of vesicle fusion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of wound healing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in prostate gland development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell shape IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of hormone secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of interleukin-1 production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of leukocyte migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to X-ray IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to estradiol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to interleukin-1 IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to peptide hormone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    annexin A1
    Names
    annexin I
    annexin-1
    calcium-dependent membrane binding protein annexin I
    calpactin II
    calpactin-2
    chromobindin-9
    lipocortin I
    phospholipase A2 inhibitory protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_206906.2 → NP_996789.2  annexin A1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000094
      UniProtKB/TrEMBL
      A0A8V0YMS3
      Related
      ENSGALP00010019931.1, ENSGALT00010033899.1
      Conserved Domains (1) summary
      smart00335
      Location:54 → 106
      ANX; Annexin repeats

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      36635449..36653095
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      36635449..36653095
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q92108.1 GenPept UniProtKB/Swiss-Prot:Q92108

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials