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    TFF2 trefoil factor 2 [ Sus scrofa (pig) ]

    Gene ID: 397420, updated on 17-Aug-2024

    Summary

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    Official Symbol
    TFF2provided by VGNC
    Official Full Name
    trefoil factor 2provided by VGNC
    Primary source
    VGNC:VGNC:93920
    See related
    Ensembl:ENSSSCG00000024320
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Also known as
    PSP; SML1
    Expression
    Biased expression in ovary (RPKM 1.9), mixtures (RPKM 0.2) and 2 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See TFF2 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 13 NC_010455.5 (205669014..205672319, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 13 NC_010455.4 (216071494..216074772, complement)

    Chromosome 13 - NC_010455.5Genomic Context describing neighboring genes Neighboring gene ATP binding cassette subfamily G member 1 Neighboring gene trefoil factor 3 Neighboring gene trefoil factor 1 Neighboring gene transmembrane serine protease 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Structure of porcine pancreatic spasmolytic polypeptide at 1.95 A resolution. Petersen TN, et al. Acta Crystallogr D Biol Crystallogr, 1996 Jul 1. PMID 15299636
    2. Crystal structure of a disulfide-linked "trefoil" motif found in a large family of putative growth factors. De A, et al. Proc Natl Acad Sci U S A, 1994 Feb 1. PMID 8302836, Free PMC Article
    3. Solution structure of a trefoil-motif-containing cell growth factor, porcine spasmolytic protein. Carr MD, et al. Proc Natl Acad Sci U S A, 1994 Mar 15. PMID 8134374, Free PMC Article
    4. Pancreatic spasmolytic polypeptide: first three-dimensional structure of a member of the mammalian trefoil family of peptides. Gajhede M, et al. Structure, 1993 Dec 15. PMID 8081739
    5. The amino acid sequence of pancreatic spasmolytic polypeptide. Thim L, et al. Biochim Biophys Acta, 1985 Mar 1. PMID 2857575

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables CXCR4 chemokine receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chemokine-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in maintenance of gastrointestinal epithelium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of gastric acid secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    trefoil factor 2
    Names
    pancreatic spasmolytic polypeptide

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010455.5 Reference Sscrofa11.1 Primary Assembly

      Range
      205669014..205672319 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003358971.3 → XP_003359019.2  trefoil factor 2

      UniProtKB/TrEMBL
      A0A4X1TI83, A0A8D1L5W7, I3LMK2
      Related
      ENSSSCP00000025323.2, ENSSSCT00000027977.3
      Conserved Domains (1) summary
      smart00018
      Location:115 → 157
      PD; P or trefoil or TFF domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P01359.4 GenPept UniProtKB/Swiss-Prot:P01359

    Gene LinkOut

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