EYA2 EYA transcriptional coactivator and phosphatase 2 [Gallus gallus (chicken)] - Gene

Summary

Symbol: EYA2provided by CGNC
Full Name: EYA transcriptional coactivator and phosphatase 2provided by CGNC
Primary source: CGNC:49455
See related: Ensembl:ENSGALG00010023863
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 21

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	20	NC_052551.1 (6011302..6104491)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	20	NC_052592.1 (5804684..5897543)

Chromosome 20 - NC_052551.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

4 hours posttreatment, Eya2 expression in dermomyotomal cells is down-regulated in Cd-exposed chick embryos. Eya2 down-regulation during the critical period of early embryogenesis may promote omphalocele by interfering with somite-derived cell migration.
Title: Eya1 and Eya2 gene expression is down-regulated during somitic myogenesis in the cadmium-induced omphalocele chick model.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein tyrosine phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in multicellular organism development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of DNA repair	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: eyes absent homolog 2

Names: eyes absent 2

NP_990246.2

EC 3.1.3.48

XP_015152203.2

EC 3.1.3.48

XP_024997931.1

EC 3.1.3.48

XP_024997932.1

EC 3.1.3.48

XP_024997933.1

EC 3.1.3.48

XP_024997934.1

EC 3.1.3.48

XP_024997935.2

EC 3.1.3.48

XP_024997936.1

EC 3.1.3.48

XP_024997937.1

EC 3.1.3.48

XP_024997939.1

EC 3.1.3.48

XP_024997940.1

EC 3.1.3.48

XP_024997941.1

EC 3.1.3.48

XP_024997943.1

EC 3.1.3.48

XP_040506573.1

EC 3.1.3.48

XP_040506574.1

EC 3.1.3.48

XP_040506576.1

EC 3.1.3.48

XP_046786531.1

EC 3.1.3.48

XP_046786532.1

EC 3.1.3.48

XP_046786533.1

EC 3.1.3.48

XP_046786534.1

EC 3.1.3.48

XP_046786535.1

EC 3.1.3.48

XP_046786536.1

EC 3.1.3.48

XP_046786537.1

EC 3.1.3.48

XP_046786538.1

EC 3.1.3.48

XP_046786539.1

EC 3.1.3.48

XP_046786540.1

EC 3.1.3.48

XP_046786541.1

EC 3.1.3.48

XP_046786542.1

EC 3.1.3.48

XP_046786543.1

EC 3.1.3.48

XP_046786544.1

EC 3.1.3.48

XP_046786545.1

EC 3.1.3.48

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_204915.2 → NP_990246.2 eyes absent homolog 2

Status: PROVISIONAL

Source sequence(s)

JAENSK010000328

UniProtKB/TrEMBL

A0A8V0ZPG9

Related

ENSGALP00010035349.1, ENSGALT00010058194.1

Conserved Domains (1) summary

cd02601
Location:263 → 534

HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052551.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

6011302..6104491

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_025142163.3 → XP_024997931.1 eyes absent homolog 2 isoform X1

UniProtKB/TrEMBL

A0A8V0ZPG9, A0A8V0ZYE4

Conserved Domains (1) summary

cd02601
Location:278 → 549

HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains
XM_025142165.3 → XP_024997933.1 eyes absent homolog 2 isoform X3

UniProtKB/TrEMBL

A0A8V0ZPG9

Conserved Domains (1) summary

cd02601
Location:278 → 527

HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains
XM_025142166.3 → XP_024997934.1 eyes absent homolog 2 isoform X4

UniProtKB/TrEMBL

A0A8V0ZPG9

Conserved Domains (1) summary

cd02601
Location:260 → 529

HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains
XM_025142164.3 → XP_024997932.1 eyes absent homolog 2 isoform X2

UniProtKB/TrEMBL

A0A8V0ZPG9

Related

ENSGALP00010035351.1, ENSGALT00010058196.1

Conserved Domains (1) summary

cd02601
Location:263 → 534

HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains
XM_025142168.3 → XP_024997936.1 eyes absent homolog 2 isoform X1

UniProtKB/TrEMBL

A0A8V0ZPG9, A0A8V0ZYE4

Related

ENSGALP00010035346.1, ENSGALT00010058190.1

Conserved Domains (1) summary

cd02601
Location:278 → 549

HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains
XM_025142172.3 → XP_024997940.1 eyes absent homolog 2 isoform X7

UniProtKB/TrEMBL

A0A8V1A290

Conserved Domains (1) summary

cd02601
Location:239 → 510

HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains
XM_040650639.2 → XP_040506573.1 eyes absent homolog 2 isoform X5

UniProtKB/TrEMBL

A0A8V0ZPG9

Conserved Domains (1) summary

cd02601
Location:263 → 512

HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains
XM_040650640.2 → XP_040506574.1 eyes absent homolog 2 isoform X6

UniProtKB/TrEMBL

A0A8V0ZPG9

Conserved Domains (1) summary

cd02601
Location:245 → 514

HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains
XM_025142167.3 → XP_024997935.2 eyes absent homolog 2 isoform X1

UniProtKB/TrEMBL

A0A8V0ZYE4
XM_015296717.4 → XP_015152203.2 eyes absent homolog 2 isoform X2

Related

ENSGALP00010035333.1, ENSGALT00010058175.1
XM_025142169.3 → XP_024997937.1 eyes absent homolog 2 isoform X1

UniProtKB/TrEMBL

A0A8V0ZPG9, A0A8V0ZYE4

Conserved Domains (1) summary

cd02601
Location:278 → 549

HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains
XM_025142171.3 → XP_024997939.1 eyes absent homolog 2 isoform X2

UniProtKB/TrEMBL

A0A8V0ZPG9

Conserved Domains (1) summary

cd02601
Location:263 → 534

HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains
XM_025142173.3 → XP_024997941.1 eyes absent homolog 2 isoform X8

UniProtKB/TrEMBL

A0A8V1A290

Conserved Domains (1) summary

cd02601
Location:226 → 497

HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains
XM_040650642.2 → XP_040506576.1 eyes absent homolog 2 isoform X9

UniProtKB/TrEMBL

A0A8V1A290

Conserved Domains (1) summary

cd02601
Location:205 → 476

HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains
XM_025142175.3 → XP_024997943.1 eyes absent homolog 2 isoform X10

UniProtKB/TrEMBL

A0A8V1A290

Conserved Domains (1) summary

cd02601
Location:197 → 468

HAD_Eya; protein tyrosine phosphatase domain of the nuclear transcription factor of Eyes absent (Eya) and related phosphatase domains