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    RpL18 Ribosomal protein L18 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38794, updated on 2-Nov-2024

    Summary

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    Official Symbol
    RpL18provided by FlyBase
    Official Full Name
    Ribosomal protein L18provided by FlyBase
    Primary source
    FLYBASE:FBgn0035753
    Locus tag
    Dmel_CG8615
    See related
    AllianceGenome:FB:FBgn0035753
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8615; Dmel\CG8615; L18e; Rp L18; RpL18e
    Summary
    A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Located in cytosolic ribosome. Is expressed in adult head; adult heart; and organism. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 18. Orthologous to human RPL18 (ribosomal protein L18). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See RpL18 in Genome Data Viewer
    Location:
    65E9-65E9; 3-19 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (7240203..7241351, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (7233303..7234451, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Birt-Hogg-Dube Neighboring gene Neosin Neighboring gene mitochondrial ribosomal protein L50 Neighboring gene meiotic P22

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome HDA PubMed 
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in cytoplasmic translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in cytosolic ribosome HDA PubMed 
    located_in cytosolic ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal protein L18
    Names
    CG8615-PA
    CG8615-PB
    CG8615-PC
    RpL18-PA
    RpL18-PB
    RpL18-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      7240203..7241351 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139834.3 → NP_648091.1  ribosomal protein L18, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648091.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VS34
      UniProtKB/TrEMBL
      M9PHM6
      Related
      FBpp0076602
      Conserved Domains (1) summary
      pfam17135
      Location:2 → 188
      Ribosomal_L18; Ribosomal protein 60S L18 and 50S L18e

    2. NM_001274572.1 → NP_001261501.1  ribosomal protein L18, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261501.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VS34
      UniProtKB/TrEMBL
      M9PHM6
      Conserved Domains (1) summary
      pfam17135
      Location:2 → 188
      Ribosomal_L18; Ribosomal protein 60S L18 and 50S L18e

    3. NM_001300037.1 → NP_001286966.1  ribosomal protein L18, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286966.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VS34
      UniProtKB/TrEMBL
      M9PHM6
      Conserved Domains (1) summary
      pfam17135
      Location:2 → 188
      Ribosomal_L18; Ribosomal protein 60S L18 and 50S L18e
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PHM6 M9PHM6
    Q9VS34.1 Q9VS34

    Gene LinkOut

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