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    M2 matrix protein 2 [ Influenza A virus (A/goose/Guangdong/1/1996(H5N1)) ]

    Gene ID: 3654621, updated on 18-Aug-2023

    Summary

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    Gene symbol
    M2
    Gene description
    matrix protein 2
    Locus tag
    FLUAVH5N1_s7gp1
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Influenza A virus (A/goose/Guangdong/1/1996(H5N1)) (strain: A/goose/Guangdong/1/1996, serotype: H5N1)
    Lineage
    Viruses; ssRNA viruses; ssRNA negative-strand viruses; Orthomyxoviridae; Influenzavirus A
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    Genomic context

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    Location:
    segment: 7
    Sequence:
    NC_007363.1 (26..1007)

    NC_007363.1Genomic Context describing neighboring genes Neighboring gene matrix protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_007363.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The nucleoprotein and matrix protein segments of H5N1 influenza viruses are responsible for dominance in embryonated eggs. Shimizu K, et al. J Gen Virol, 2011 Jul. PMID 21471324, Free PMC Article
    2. Contributions of the avian influenza virus HA, NA, and M2 surface proteins to the induction of neutralizing antibodies and protective immunity. Nayak B, et al. J Virol, 2010 Mar. PMID 20032181, Free PMC Article
    3. Evolution of H5N1 avian influenza viruses in Asia. World Health Organization Global Influenza Program Surveillance Network. Emerg Infect Dis, 2005 Oct. PMID 16318689, Free PMC Article
    4. Genetic characterization of the pathogenic influenza A/Goose/Guangdong/1/96 (H5N1) virus: similarity of its hemagglutinin gene to those of H5N1 viruses from the 1997 outbreaks in Hong Kong. Xu X, et al. Virology, 1999 Aug 15. PMID 10484749

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. NP, M1 and M2 segments of H5N1 influenza viruses are responsible for viral dominance.
      Title: The nucleoprotein and matrix protein segments of H5N1 influenza viruses are responsible for dominance in embryonated eggs.
    2. Results describe the individual contributions of each of the three HPAIV surface proteins -- hemagglutinin (HA), neuraminidase (NA), and M2 -- to the induction of HPAIV-neutralizing serum antibodies and protective immunity in chickens.
      Title: Contributions of the avian influenza virus HA, NA, and M2 surface proteins to the induction of neutralizing antibodies and protective immunity.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    matrix protein 2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_007363.1 Reference assembly

      Range
      26..1007
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_308670.1 matrix protein 2 [Influenza A virus (A/goose/Guangdong/1/1996(H5N1))]

      See identical proteins and their annotated locations for YP_308670.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P0C5T0, Q9Q0L9
      UniProtKB/TrEMBL
      A0A2C7, A4Q8F4, D5XLQ6, D9I718, L7YNL0
      Conserved Domains (1) summary
      pfam00599
      Location:1 → 97
      Flu_M2; Influenza Matrix protein (M2)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9Q0L9.1

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