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    Gemin8 gem (nuclear organelle) associated protein 8 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363462, updated on 2-Nov-2024

    Summary

    Official Symbol
    Gemin8provided by RGD
    Official Full Name
    gem (nuclear organelle) associated protein 8provided by RGD
    Primary source
    RGD:1359160
    See related
    EnsemblRapid:ENSRNOG00000029038 AllianceGenome:RGD:1359160
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam51a1
    Summary
    Predicted to be involved in spliceosomal snRNP assembly. Predicted to be located in cytosol and nucleus. Predicted to be part of SMN complex. Orthologous to human GEMIN8 (gem nuclear organelle associated protein 8). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 68.0), Brain (RPKM 66.5) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Gemin8 in Genome Data Viewer
    Location:
    Xq14
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (31891446..31910280, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (28259806..28278641, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (29806605..29825439, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene trafficking protein particle complex subunit 2 Neighboring gene Ofd1 centriole and centriolar satellite protein Neighboring gene glycoprotein m6b Neighboring gene glycine receptor, alpha 2 Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 4, pseudogene 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Clone Names

    • MGC94189

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in spliceosomal snRNP assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in spliceosomal snRNP assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of SMN complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of SMN complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of SMN-Sm protein complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    gem-associated protein 8
    Names
    family with sequence similarity 51, member A1 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007756.1NP_001007757.1  gem-associated protein 8

      See identical proteins and their annotated locations for NP_001007757.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079160
      UniProtKB/TrEMBL
      Q6AY77
      Related
      ENSRNOP00000044281.3, ENSRNOT00000048155.6
      Conserved Domains (1) summary
      pfam15348
      Location:10239
      GEMIN8; Gemini of Cajal bodies-associated protein 8

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      31891446..31910280 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)