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    Tmem150b transmembrane protein 150B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 308346, updated on 18-Sep-2024

    Summary

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    Official Symbol
    Tmem150bprovided by RGD
    Official Full Name
    transmembrane protein 150Bprovided by RGD
    Primary source
    RGD:1306181
    See related
    EnsemblRapid:ENSRNOG00000028273 AllianceGenome:RGD:1306181
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Tmem224; RGD1306181
    Summary
    Predicted to be integral component of plasma membrane. Orthologous to human TMEM150B (transmembrane protein 150B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Spleen (RPKM 57.5), Brain (RPKM 33.2) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tmem150b in Genome Data Viewer
    Location:
    1q12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (78153729..78164149)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (69124943..69134617)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (72692089..72701732)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene lysine methyltransferase 5C Neighboring gene U6 spliceosomal RNA Neighboring gene BR serine/threonine kinase 1 Neighboring gene uncharacterized LOC108349434 Neighboring gene HSPA (Hsp70) binding protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Plasticity of PI4KIIIα interactions at the plasma membrane. Chung J, et al. EMBO Rep, 2015 Mar. PMID 25608530, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in autophagy IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in autophagosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    modulator of macroautophagy TMEM150B
    Names
    transmembrane protein 224

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107476.1 → NP_001100946.1  modulator of macroautophagy TMEM150B

      See identical proteins and their annotated locations for NP_001100946.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474075
      UniProtKB/TrEMBL
      A6KNN1, D3ZEH7
      Conserved Domains (1) summary
      pfam10277
      Location:4 → 207
      Frag1; Frag1/DRAM/Sfk1 family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      78153729..78164149
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039111108.2 → XP_038967036.1  modulator of macroautophagy TMEM150B isoform X3

      Conserved Domains (1) summary
      pfam10277
      Location:4 → 108
      Frag1; Frag1/DRAM/Sfk1 family

    2. XM_039111106.2 → XP_038967034.1  modulator of macroautophagy TMEM150B isoform X2

      Conserved Domains (1) summary
      pfam10277
      Location:4 → 187
      Frag1; Frag1/DRAM/Sfk1 family

    3. XM_039111105.2 → XP_038967033.1  modulator of macroautophagy TMEM150B isoform X1

      UniProtKB/TrEMBL
      A6KNN1, D3ZEH7
      Conserved Domains (1) summary
      pfam10277
      Location:4 → 207
      Frag1; Frag1/DRAM/Sfk1 family

    4. XM_006228267.5 → XP_006228329.1  modulator of macroautophagy TMEM150B isoform X1

      See identical proteins and their annotated locations for XP_006228329.1

      UniProtKB/TrEMBL
      A6KNN1, D3ZEH7
      Related
      ENSRNOP00000036209.3, ENSRNOT00000032439.6
      Conserved Domains (1) summary
      pfam10277
      Location:4 → 207
      Frag1; Frag1/DRAM/Sfk1 family
    Nucleotide Protein Strain
    Heading Accession and Version

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