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    UL98 deoxyribonuclease [ Human betaherpesvirus 5 ]

    Gene ID: 3077527, updated on 20-Nov-2023

    Summary

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    Gene symbol
    UL98
    Gene description
    deoxyribonuclease
    Locus tag
    HHV5wtgp091
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Human betaherpesvirus 5 (strain: Merlin, acronym: HHV-5; HCMV, nat-host: Homo sapiens, culture-collection: ATCC:VR-1590)
    Lineage
    Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Herpesviridae; Betaherpesvirinae; Cytomegalovirus
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    Genomic context

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    Sequence:
    NC_006273.2 (144015..145769)

    NC_006273.2Genomic Context describing neighboring genes Neighboring gene protein UL95 Neighboring gene tegument protein UL14 Neighboring gene tegument serine/threonine protein kinase Neighboring gene myristylated tegument protein Neighboring gene envelope glycoprotein M Neighboring gene helicase-primase subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_006273.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural modelling and mutagenesis of human cytomegalovirus alkaline nuclease UL98. Kuchta AL, et al. J Gen Virol, 2012 Jan. PMID 21900421, Free PMC Article
    2. High-resolution human cytomegalovirus transcriptome. Gatherer D, et al. Proc Natl Acad Sci U S A, 2011 Dec 6. PMID 22109557, Free PMC Article
    3. Genetic content of wild-type human cytomegalovirus. Dolan A, et al. J Gen Virol, 2004 May. PMID 15105547
    4. The most abundantly transcribed human cytomegalovirus gene (beta 2.7) is non-essential for growth in vitro. McSharry BP, et al. J Gen Virol, 2003 Sep. PMID 12917473
    5. Two novel spliced genes in human cytomegalovirus. Akter P, et al. J Gen Virol, 2003 May. PMID 12692276

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Amino acid substitutions D254A, E278A, K280A and S252A in UL98 virtually eliminated exo and endo activities.
      Title: Structural modelling and mutagenesis of human cytomegalovirus alkaline nuclease UL98.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    • core gene

    General protein information

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    Preferred Names
    deoxyribonuclease

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_006273.2 Reference assembly

      Range
      144015..145769
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_081545.1 deoxyribonuclease [Human betaherpesvirus 5]

      See identical proteins and their annotated locations for YP_081545.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      F5HF49, P16789, Q7M6J3
      UniProtKB/TrEMBL
      A0A0G2TED5, A0A0G2TFL8, A0A0G2TH17, A0A0R5ECY3, A8T7I4, B8YEC2, B9VXQ5, C8BL41, D2K3Q5, D3YS21, Q6SW45, Q99D32, V9LLZ4, V9LSD5
      Conserved Domains (1) summary
      pfam01771
      Location:18 → 570
      Herpes_alk_exo; Herpesvirus alkaline exonuclease
    Nucleotide Protein
    Heading Accession and Version

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