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    Eif1ad eukaryotic translation initiation factor 1A domain containing [ Rattus norvegicus (Norway rat) ]

    Gene ID: 293673, updated on 2-Nov-2024

    Summary

    Official Symbol
    Eif1adprovided by RGD
    Official Full Name
    eukaryotic translation initiation factor 1A domain containingprovided by RGD
    Primary source
    RGD:1304686
    See related
    EnsemblRapid:ENSRNOG00000020463 AllianceGenome:RGD:1304686
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1304686
    Summary
    Predicted to enable RNA binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to human EIF1AD (eukaryotic translation initiation factor 1A domain containing). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Thymus (RPKM 118.5), Spleen (RPKM 97.4) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Eif1ad in Genome Data Viewer
    Location:
    1q43
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (212103715..212109015)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (202674362..202679662)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (220746387..220751687)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene cystatin E/M Neighboring gene barrier to autointegration nuclear assembly factor 1 Neighboring gene spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP Neighboring gene uncharacterized LOC134483957 Neighboring gene testis specific 10 interacting protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Clone Names

    • MGC94083

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables translation initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in translational initiation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    probable RNA-binding protein EIF1AD
    Names
    eukaryotic translation initiation factor 1A domain-containing protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001008305.1NP_001008306.1  probable RNA-binding protein EIF1AD

      See identical proteins and their annotated locations for NP_001008306.1

      Status: PROVISIONAL

      Source sequence(s)
      BC085818
      UniProtKB/Swiss-Prot
      Q5RKI6
      UniProtKB/TrEMBL
      A6HZ44
      Related
      ENSRNOP00000027752.3, ENSRNOT00000027753.7
      Conserved Domains (1) summary
      cd05792
      Location:25102
      S1_eIF1AD_like; S1_eIF1AD_like: eukaryotic translation initiation factor 1A domain containing protein (eIF1AD)-like, S1-like RNA-binding domain. eIF1AD is also known as MGC11102 protein. Little is known about the function of eIF1AD. S1-like RNA-binding domains are found ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      212103715..212109015
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039108337.2XP_038964265.1  probable RNA-binding protein EIF1AD isoform X1

      UniProtKB/TrEMBL
      A6HZ45
      Conserved Domains (1) summary
      cl09927
      Location:150
      S1_like; Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain. Both domains ...