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    Tp53i13 tumor protein p53 inducible protein 13 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287550, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Tp53i13provided by RGD
    Official Full Name
    tumor protein p53 inducible protein 13provided by RGD
    Primary source
    RGD:1559818
    See related
    EnsemblRapid:ENSRNOG00000022615 AllianceGenome:RGD:1559818
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Trp53i13; RGD1559818
    Summary
    Predicted to be involved in several processes, including negative regulation of cell cycle; response to UV; and response to xenobiotic stimulus. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm. Orthologous to human TP53I13 (tumor protein p53 inducible protein 13). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Heart (RPKM 79.2), Lung (RPKM 73.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tp53i13 in Genome Data Viewer
    Location:
    10q24
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (62854851..62861241, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (62356722..62363122, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (62650640..62655327)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 13B Neighboring gene uncharacterized LOC120095265 Neighboring gene GIT ArfGAP 1 Neighboring gene abhydrolase domain containing 15 Neighboring gene TAO kinase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. DSCP1, a novel TP53-inducible gene, is upregulated by strong genotoxic stresses and its overexpression inhibits tumor cell growth in vitro. Hata T, et al. Int J Oncol, 2004 Mar. PMID 14767535
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in negative regulation of cell cycle ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in response to UV ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in response to organic cyclic compound ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in response to xenobiotic stimulus ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tumor protein p53-inducible protein 13
    Names
    transformation related protein 53 inducible protein 13

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105818.1 → NP_001099288.1  tumor protein p53-inducible protein 13 precursor

      See identical proteins and their annotated locations for NP_001099288.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473948
      UniProtKB/Swiss-Prot
      B0BN44
      UniProtKB/TrEMBL
      A6HGY3
      Related
      ENSRNOP00000010691.6, ENSRNOT00000010691.8

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      62854851..62861241 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039085537.2 → XP_038941465.1  tumor protein p53-inducible protein 13 isoform X2

      UniProtKB/TrEMBL
      A6HGY4

    2. XM_063268685.1 → XP_063124755.1  tumor protein p53-inducible protein 13 isoform X2

      UniProtKB/TrEMBL
      A6HGY4

    3. XM_063268684.1 → XP_063124754.1  tumor protein p53-inducible protein 13 isoform X2

      UniProtKB/TrEMBL
      A6HGY4

    4. XM_006246902.5 → XP_006246964.1  tumor protein p53-inducible protein 13 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZWV6
      Related
      ENSRNOP00000083262.1, ENSRNOT00000094189.2
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B0BN44.1 GenPept UniProtKB/Swiss-Prot:B0BN44

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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