Klra16 killer cell lectin-like receptor, subfamily A, member 16 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Klra16provided by MGI
Official Full Name: killer cell lectin-like receptor, subfamily A, member 16provided by MGI
Primary source: MGI:MGI:1351669
See related: AllianceGenome:MGI:1351669
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Ly49P; Ly49x; Klra24; Ly-49P
Summary: Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
Annotation information: not in current annotation release
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Genomic context

Location:: 6; 6 F3

Annotation release	Status	Assembly	Chr	Location
108.20200622	latest, but not current	GRCm38.p6 (GCF_000001635.26)	6 (PATCHES)	NW_006763130.1 (149512..173164, complement)
108.20200622	latest, but not current	GRCm38.p6 (GCF_000001635.26)	6 Unlocalized Scaffold (NOD/ShiLtJ)	NT_187002.1 (687152..883151, complement)

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data indicate deleterious effects of interferon gamma (IFN-gamma) in regulating NK cell Ly-49 receptors during pregnancy failure.
Title: IFN-γ modulates Ly-49 receptors on NK cells in IFN-γ-induced pregnancy failure.
The activating Ly49P receptor recognizes cells infected with mouse cytomegalovirus (MCMV) by a process that requires the presence of H2-D(k) and the MCMV m04 protein.
Title: Ly49P recognition of cytomegalovirus-infected cells expressing H2-Dk and CMV-encoded m04 correlates with the NK cell antiviral response.

Submit: New GeneRIF Correction

General gene information

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Markers

NoName (e-PCR)
- UniSTS:495402

Klra1 (e-PCR), detects polymorphism
- UniSTS:143704

Klra1 (e-PCR), detects polymorphism
- UniSTS:143706

Klra4 (e-PCR), detects polymorphism
- UniSTS:143712

NoName (e-PCR)
- UniSTS:494960

Gene Ontology Provided by MGI

Component	Evidence Code	Pubs
located_in plasma membrane	TAS Traceable Author Statement more info	PubMed

General protein information

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Preferred Names: killer cell lectin-like receptor, subfamily A, member 16

Names: Ly49X receptor; natural killer cell receptor Ly-49P3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_013794.4 → NP_038822.3 killer cell lectin-like receptor, subfamily A, member 16

See identical proteins and their annotated locations for NP_038822.3

Status: PROVISIONAL

Source sequence(s)

AF146570

UniProtKB/TrEMBL

Q4Z8P4, Q9QZY1

Conserved Domains (2) summary

cd03593
Location:143 → 256

CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

pfam08391
Location:40 → 154

Ly49; Ly49-like protein, N-terminal region