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    Rps26 ribosomal protein S26 [ Mus musculus (house mouse) ]

    Gene ID: 27370, updated on 2-Nov-2024

    Summary

    Official Symbol
    Rps26provided by MGI
    Official Full Name
    ribosomal protein S26provided by MGI
    Primary source
    MGI:MGI:1351628
    See related
    Ensembl:ENSMUSG00000025362 AllianceGenome:MGI:1351628
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation and negative regulation of RNA splicing. Part of cytosolic small ribosomal subunit. Is active in synapse. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 10. Orthologous to human RPS26 (ribosomal protein S26). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in liver E14.5 (RPKM 610.3), liver E14 (RPKM 580.0) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Rps26 in Genome Data Viewer
    Location:
    10 D3; 10 77.11 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (128460398..128462375, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (128624529..128626506, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene erb-b2 receptor tyrosine kinase 3 Neighboring gene microRNA 6917 Neighboring gene STARR-seq mESC enhancer starr_28288 Neighboring gene STARR-positive B cell enhancer ABC_E10660 Neighboring gene STARR-positive B cell enhancer ABC_E5200 Neighboring gene predicted gene 9182 Neighboring gene STARR-positive B cell enhancer ABC_E904 Neighboring gene IKAROS family zinc finger 4 Neighboring gene predicted gene, 26876 Neighboring gene predicted gene, 51824

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (4)  1 citation

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables mRNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables mRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cytoplasmic translation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cytoplasmic translation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in negative regulation of RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of RNA splicing ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in translation at postsynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in translation at presynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in cytoplasmic side of rough endoplasmic reticulum membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of cytosolic small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    part_of cytosolic small ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of cytosolic small ribosomal subunit NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in postsynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in presynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in ribosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in ribosome NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    is_active_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    small ribosomal subunit protein eS26
    Names
    40S ribosomal protein S26

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013765.2NP_038793.2  small ribosomal subunit protein eS26

      See identical proteins and their annotated locations for NP_038793.2

      Status: VALIDATED

      Source sequence(s)
      AK012722, AV585706, BU530648
      Consensus CDS
      CCDS36090.1
      UniProtKB/Swiss-Prot
      P62855
      UniProtKB/TrEMBL
      Q497N1
      Related
      ENSMUSP00000026420.6, ENSMUST00000026420.7
      Conserved Domains (1) summary
      pfam01283
      Location:1101
      Ribosomal_S26e; Ribosomal protein S26e

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      128460398..128462375 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)