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    Tmem255b transmembrane protein 255B [ Mus musculus (house mouse) ]

    Gene ID: 272465, updated on 28-Oct-2024

    Summary

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    Official Symbol
    Tmem255bprovided by MGI
    Official Full Name
    transmembrane protein 255Bprovided by MGI
    Primary source
    MGI:MGI:2685533
    See related
    Ensembl:ENSMUSG00000038457 AllianceGenome:MGI:2685533
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm687; Fam70b
    Summary
    Predicted to be located in membrane. Is expressed in utricle and vagus ganglion. Orthologous to human TMEM255B (transmembrane protein 255B). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Broad expression in ovary adult (RPKM 1.7), mammary gland adult (RPKM 1.2) and 19 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Tmem255b in Genome Data Viewer
    Location:
    8 A1.1; 8 6.0 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (13485118..13543434)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (13435113..13493434)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene ATPase, H+/K+ exchanging, beta polypeptide Neighboring gene G protein-coupled receptor kinase 1 Neighboring gene growth arrest specific 6 Neighboring gene predicted gene, 53399 Neighboring gene RIKEN cDNA 1700029H14 gene Neighboring gene STARR-seq mESC enhancer starr_20769 Neighboring gene RAS p21 protein activator 3 Neighboring gene predicted gene, 34795

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    General gene information

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    Homology

    Clone Names

    • FLJ20716

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 255B
    Names
    family with sequence similarity 70, member B
    protein FAM70B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001143671.1 → NP_001137143.1  transmembrane protein 255B isoform 1

      See identical proteins and their annotated locations for NP_001137143.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK131817, BC089620
      Consensus CDS
      CCDS52486.1
      UniProtKB/TrEMBL
      G3UWB7
      Related
      ENSMUSP00000130504.2, ENSMUST00000167505.3
      Conserved Domains (2) summary
      pfam13273
      Location:31 → 104
      DUF4064; Protein of unknown function (DUF4064)
      pfam14967
      Location:16 → 327
      FAM70; FAM70 protein

    2. NM_001143672.1 → NP_001137144.1  transmembrane protein 255B isoform 2

      See identical proteins and their annotated locations for NP_001137144.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region, compared to variant 1. The encoded protein (isoform 2) has a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AK131817, BC089620
      Consensus CDS
      CCDS52487.1
      UniProtKB/TrEMBL
      G5E908
      Related
      ENSMUSP00000127421.2, ENSMUST00000167071.9
      Conserved Domains (1) summary
      pfam14967
      Location:16 → 306
      FAM70; FAM70 protein

    3. NM_001402814.1 → NP_001389743.1  transmembrane protein 255B isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC130818

    4. NM_001402815.1 → NP_001389744.1  transmembrane protein 255B isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC130818, AC134613

    5. NM_001402816.1 → NP_001389745.1  transmembrane protein 255B isoform 5 precursor

      Status: VALIDATED

      Source sequence(s)
      AC130818

    6. NM_001402817.1 → NP_001389746.1  transmembrane protein 255B isoform 6 precursor

      Status: VALIDATED

      Source sequence(s)
      AC130818, AC134613

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      13485118..13543434
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006508813.5 → XP_006508876.1  transmembrane protein 255B isoform X3

      Conserved Domains (1) summary
      pfam14967
      Location:1 → 188
      FAM70; FAM70 protein

    2. XM_006508811.5 → XP_006508874.1  transmembrane protein 255B isoform X2

      Conserved Domains (1) summary
      pfam14967
      Location:16 → 253
      FAM70; FAM70 protein

    3. XM_006508814.5 → XP_006508877.1  transmembrane protein 255B isoform X4

      Conserved Domains (1) summary
      pfam14967
      Location:16 → 275
      FAM70; FAM70 protein

    RNA

    1. XR_004934836.1 RNA Sequence

    2. XR_003947295.2 RNA Sequence

    3. XR_004934837.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5FW56.3 GenPept UniProtKB/Swiss-Prot:Q5FW56

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials