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    Nat14 N-acetyltransferase 14 [ Mus musculus (house mouse) ]

    Gene ID: 269854, updated on 2-Nov-2024

    Summary

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    Official Symbol
    Nat14provided by MGI
    Official Full Name
    N-acetyltransferase 14provided by MGI
    Primary source
    MGI:MGI:3039561
    See related
    Ensembl:ENSMUSG00000035285 AllianceGenome:MGI:3039561
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable N-acetyltransferase activity. Predicted to be located in membrane. Orthologous to human NAT14 (N-acetyltransferase 14 (putative)). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in frontal lobe adult (RPKM 13.5), cortex adult (RPKM 11.9) and 23 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Nat14 in Genome Data Viewer
    Location:
    7 A1; 7 2.85 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (4925250..4928005)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (4918877..4925006)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene 3-phosphoglycerate dehydrogenase pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E10424 Neighboring gene zinc finger protein 628 Neighboring gene microRNA 12202 Neighboring gene scavenger receptor cysteine rich family, 5 domains Neighboring gene STARR-positive B cell enhancer ABC_E6508 Neighboring gene SH3-binding domain kinase family, member 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Molecular identification of aspartate N-acetyltransferase and its mutation in hypoacetylaspartia. Wiame E, et al. Biochem J, 2009 Dec 14. PMID 19807691
    2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Results indicated that NAT8L, but not NAT14, catalysed the synthesis of NAA from L-aspartate and acetyl-CoA.
      Title: Molecular identification of aspartate N-acetyltransferase and its mutation in hypoacetylaspartia.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC57098

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables N-acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    probable N-acetyltransferase 14
    NP_001345810.1
    NP_001345811.1
    NP_001345812.1
    NP_001345813.1
    NP_958743.1
    XP_006540084.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001358881.1 → NP_001345810.1  probable N-acetyltransferase 14

      Status: VALIDATED

      Source sequence(s)
      AC157563
      Consensus CDS
      CCDS20749.1
      UniProtKB/Swiss-Prot
      Q8BVG8

    2. NM_001358882.1 → NP_001345811.1  probable N-acetyltransferase 14

      Status: VALIDATED

      Source sequence(s)
      AC157563
      Consensus CDS
      CCDS20749.1
      UniProtKB/Swiss-Prot
      Q8BVG8
      Related
      ENSMUSP00000147229.2, ENSMUST00000207687.2

    3. NM_001358883.1 → NP_001345812.1  probable N-acetyltransferase 14

      Status: VALIDATED

      Source sequence(s)
      AC157563
      Consensus CDS
      CCDS20749.1
      UniProtKB/Swiss-Prot
      Q8BVG8

    4. NM_001358884.1 → NP_001345813.1  probable N-acetyltransferase 14

      Status: VALIDATED

      Source sequence(s)
      AC157563
      Consensus CDS
      CCDS20749.1
      UniProtKB/Swiss-Prot
      Q8BVG8

    5. NM_201355.3 → NP_958743.1  probable N-acetyltransferase 14

      See identical proteins and their annotated locations for NP_958743.1

      Status: VALIDATED

      Source sequence(s)
      AK158627
      Consensus CDS
      CCDS20749.1
      UniProtKB/Swiss-Prot
      Q8BVG8
      Related
      ENSMUSP00000045354.6, ENSMUST00000047309.6

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      4925250..4928005
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006540021.1 → XP_006540084.1  probable N-acetyltransferase 14 isoform X1

      See identical proteins and their annotated locations for XP_006540084.1

      UniProtKB/Swiss-Prot
      Q8BVG8
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BVG8.1 GenPept UniProtKB/Swiss-Prot:Q8BVG8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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