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    RAI14 retinoic acid induced 14 [ Homo sapiens (human) ]

    Gene ID: 26064, updated on 3-Nov-2024

    Summary

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    Official Symbol
    RAI14provided by HGNC
    Official Full Name
    retinoic acid induced 14provided by HGNC
    Primary source
    HGNC:HGNC:14873
    See related
    Ensembl:ENSG00000039560 MIM:606586; AllianceGenome:HGNC:14873
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    RAI13; NORPEG
    Summary
    Predicted to be involved in cell differentiation and spermatogenesis. Located in cytosol; fibrillar center; and nucleoplasm. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in endometrium (RPKM 27.5), placenta (RPKM 14.1) and 23 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See RAI14 in Genome Data Viewer
    Location:
    5p13.2
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (34656328..34832612)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (34903424..35079712)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (34656433..34832717)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105374721 Neighboring gene Sharpr-MPRA regulatory region 6534 Neighboring gene ReSE screen-validated silencer GRCh37_chr5:34621050-34621410 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15966 Neighboring gene RAI14 divergent transcript Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:34700297-34700798 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:34700799-34701298 Neighboring gene uncharacterized LOC124900960 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:34721500-34722000 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:34722001-34722501 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:34735806-34736306 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:34736307-34736807 Neighboring gene NANOG hESC enhancer GRCh37_chr5:34736814-34737353 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22465 Neighboring gene MPRA-validated peak5222 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22466 Neighboring gene uncharacterized LOC124900959 Neighboring gene TTC23L antisense RNA 1 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr5:34866693-34867892 Neighboring gene tetratricopeptide repeat domain 23 like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Retinoic acid-induced protein 14 links mechanical forces to Hippo signaling. Jeong W, et al. EMBO Rep, 2024 Sep. PMID 39160347, Free PMC Article
    2. RAI14 Promotes Melanoma Progression by Regulating the FBXO32/c-MYC Pathway. Xu J, et al. Int J Mol Sci, 2022 Oct 10. PMID 36233342, Free PMC Article
    3. Expression of a novel alternative transcript of the novel retinal pigment epithelial cell gene NORPEG in human testes. Yuan W, et al. Asian J Androl, 2005 Sep. PMID 16110356
    4. Cell density-dependent nuclear/cytoplasmic localization of NORPEG (RAI14) protein. Kutty RK, et al. Biochem Biophys Res Commun, 2006 Jul 14. PMID 16729964
    5. High Expression of Retinoic Acid Induced 14 (RAI14) in Gastric Cancer and Its Prognostic Value. He XY, et al. Med Sci Monit, 2018 Apr 14. PMID 29654694, Free PMC Article

    See all (131) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Retinoic acid-induced protein 14 links mechanical forces to Hippo signaling.
      Title: Retinoic acid-induced protein 14 links mechanical forces to Hippo signaling.
    2. Phenotypic Heterogeneity Analysis of APC-Mutant Colon Cancer by Proteomics and Phosphoproteomics Identifies RAI14 as a Key Prognostic Determinant in East Asians and Westerners.
      Title: Phenotypic Heterogeneity Analysis of APC-Mutant Colon Cancer by Proteomics and Phosphoproteomics Identifies RAI14 as a Key Prognostic Determinant in East Asians and Westerners.
    3. The dual-crosslinked prospective values of RAI14 for the diagnosis and chemosurveillance in triple negative breast cancer.
      Title: The dual-crosslinked prospective values of RAI14 for the diagnosis and chemosurveillance in triple negative breast cancer.
    4. The deubiquitinating enzyme STAMBP is a newly discovered driver of triple-negative breast cancer progression that maintains RAI14 protein stability.
      Title: The deubiquitinating enzyme STAMBP is a newly discovered driver of triple-negative breast cancer progression that maintains RAI14 protein stability.
    5. RAI14 Promotes Melanoma Progression by Regulating the FBXO32/c-MYC Pathway.
      Title: RAI14 Promotes Melanoma Progression by Regulating the FBXO32/c-MYC Pathway.
    6. These findings provide significant insight into the role of RAI14 in mTOR-induced glial inflammation, which is closely associated with infection and ischemia stimuli.
      Title: Retinoic Acid-Induced Protein 14 (RAI14) Promotes mTOR-Mediated Inflammation Under Inflammatory Stress and Chemical Hypoxia in a U87 Glioblastoma Cell Line.
    7. TCGA database and Kaplan-Meier Plotter mining results showed that compared to those with RAI14 low mRNA expression levels, Gastric Cancer patients with RAI14 high mRNA expression levels had remarkably lower time of both overall survival and disease-free survival. Cox multivariate survival analyses shows high expression of RAI14 was the only independent predictor of unfavorable prognosis in patients with gastric cancer.
      Title: High Expression of Retinoic Acid Induced 14 (RAI14) in Gastric Cancer and Its Prognostic Value.
    8. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
      Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    9. Subcellular localization of NORPEG in retinal pigment epithelial (ARPE-19) cells varies with cell density, with predominantly nuclear localization in nonconfluent cells, but a cytoplasmic localization in confluent cultures.
      Title: Cell density-dependent nuclear/cytoplasmic localization of NORPEG (RAI14) protein.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genome-wide association study identifies single-nucleotide polymorphism in KCNB1 associated with left ventricular mass in humans: the HyperGEN Study.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • KIAA1334, DKFZp564G013

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in anchoring junction IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cell cortex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		  
    located_in fibrillar center IDA
    Inferred from Direct Assay
    more info
    		  
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		  
    located_in stress fiber IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ankycorbin
    Names
    ankyrin repeat and coiled-coil structure-containing protein
    novel retinal pigment epithelial cell protein
    retinoic acid-induced protein 14

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001145520.1 → NP_001138992.1  ankycorbin isoform a

      See identical proteins and their annotated locations for NP_001138992.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-3 encode the same isoform (a).
      Source sequence(s)
      AB037755, AF155135, AY317139
      Consensus CDS
      CCDS34142.1
      UniProtKB/Swiss-Prot
      E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5
      Related
      ENSP00000388725.2, ENST00000428746.6
      Conserved Domains (7) summary
      PRK03918
      Location:430 → 946
      PRK03918; chromosome segregation protein; Provisional
      cd00204
      Location:81 → 205
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:123 → 215
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:23 → 73
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:118 → 149
      ANK; ANK repeat [structural motif]
      cl03075
      Location:602 → 732
      GrpE; nucleotide exchange factor GrpE
      cl19219
      Location:589 → 662
      DUF342; Protein of unknown function (DUF342)

    2. NM_001145521.2 → NP_001138993.1  ankycorbin isoform a

      See identical proteins and their annotated locations for NP_001138993.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-3 encode the same isoform (a).
      Source sequence(s)
      AF155135, AK308306, AY317139, BC028681, DB036130
      Consensus CDS
      CCDS34142.1
      UniProtKB/Swiss-Prot
      E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5
      Related
      ENSP00000422942.1, ENST00000503673.5
      Conserved Domains (7) summary
      PRK03918
      Location:430 → 946
      PRK03918; chromosome segregation protein; Provisional
      cd00204
      Location:81 → 205
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:123 → 215
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:23 → 73
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:118 → 149
      ANK; ANK repeat [structural motif]
      cl03075
      Location:602 → 732
      GrpE; nucleotide exchange factor GrpE
      cl19219
      Location:589 → 662
      DUF342; Protein of unknown function (DUF342)

    3. NM_001145522.2 → NP_001138994.1  ankycorbin isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks an alternate in-frame exon, compared to variant 1. This results in a shorter protein (isoform b), compared to isoform a.
      Source sequence(s)
      AF155135, AK314379, DA485361, DN994273
      Consensus CDS
      CCDS54837.1
      UniProtKB/Swiss-Prot
      Q9P0K7
      Related
      ENSP00000422377.1, ENST00000512629.5
      Conserved Domains (4) summary
      PHA03095
      Location:12 → 224
      PHA03095; ankyrin-like protein; Provisional
      PRK03918
      Location:401 → 917
      PRK03918; DNA double-strand break repair ATPase Rad50
      sd00045
      Location:118 → 149
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:90 → 182
      Ank_2; Ankyrin repeats (3 copies)

    4. NM_001145523.2 → NP_001138995.1  ankycorbin isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR, uses an alternate 5' coding exon, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (c) has a distinct N-terminus and is shorter than isoform a.
      Source sequence(s)
      AF155135, AY317139, AY354204
      Consensus CDS
      CCDS54838.1
      UniProtKB/Swiss-Prot
      Q9P0K7
      Related
      ENSP00000423854.1, ENST00000506376.1
      Conserved Domains (4) summary
      PHA03095
      Location:3 → 216
      PHA03095; ankyrin-like protein; Provisional
      PRK03918
      Location:422 → 938
      PRK03918; DNA double-strand break repair ATPase Rad50
      sd00045
      Location:110 → 141
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:82 → 174
      Ank_2; Ankyrin repeats (3 copies)

    5. NM_001145525.2 → NP_001138997.1  ankycorbin isoform d

      See identical proteins and their annotated locations for NP_001138997.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR, uses an alternate 5' coding exon, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (d) has a distinct N-terminus and is longer than isoform a.
      Source sequence(s)
      AF155135, AK308306, AY317139, DB036130
      Consensus CDS
      CCDS54839.1
      UniProtKB/Swiss-Prot
      Q9P0K7
      Related
      ENSP00000427123.1, ENST00000515799.5
      Conserved Domains (7) summary
      PRK03918
      Location:433 → 949
      PRK03918; chromosome segregation protein; Provisional
      cd00204
      Location:84 → 208
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:126 → 218
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:26 → 76
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:121 → 152
      ANK; ANK repeat [structural motif]
      cl03075
      Location:605 → 735
      GrpE; nucleotide exchange factor GrpE
      cl19219
      Location:592 → 665
      DUF342; Protein of unknown function (DUF342)

    6. NM_015577.3 → NP_056392.2  ankycorbin isoform a

      See identical proteins and their annotated locations for NP_056392.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the predominant isoform (a). Variants 1-3 encode the same isoform (a).
      Source sequence(s)
      AF155135, BC028681, DA485361
      Consensus CDS
      CCDS34142.1
      UniProtKB/Swiss-Prot
      E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5
      Related
      ENSP00000265109.3, ENST00000265109.8
      Conserved Domains (7) summary
      PRK03918
      Location:430 → 946
      PRK03918; chromosome segregation protein; Provisional
      cd00204
      Location:81 → 205
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:123 → 215
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:23 → 73
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:118 → 149
      ANK; ANK repeat [structural motif]
      cl03075
      Location:602 → 732
      GrpE; nucleotide exchange factor GrpE
      cl19219
      Location:589 → 662
      DUF342; Protein of unknown function (DUF342)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      34656328..34832612
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047417088.1 → XP_047273044.1  ankycorbin isoform X2

      UniProtKB/Swiss-Prot
      E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5

    2. XM_047417092.1 → XP_047273048.1  ankycorbin isoform X6

      Conserved Domains (4) summary
      PHA03095
      Location:12 → 224
      PHA03095; ankyrin-like protein; Provisional
      PRK03918
      Location:401 → 917
      PRK03918; DNA double-strand break repair ATPase Rad50
      sd00045
      Location:118 → 149
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:90 → 182
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_017009335.2 → XP_016864824.1  ankycorbin isoform X6

      UniProtKB/Swiss-Prot
      Q9P0K7
      Conserved Domains (4) summary
      PHA03095
      Location:12 → 224
      PHA03095; ankyrin-like protein; Provisional
      PRK03918
      Location:401 → 917
      PRK03918; DNA double-strand break repair ATPase Rad50
      sd00045
      Location:118 → 149
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:90 → 182
      Ank_2; Ankyrin repeats (3 copies)

    4. XM_011514021.3 → XP_011512323.1  ankycorbin isoform X2

      See identical proteins and their annotated locations for XP_011512323.1

      UniProtKB/Swiss-Prot
      E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5
      Conserved Domains (7) summary
      PRK03918
      Location:430 → 946
      PRK03918; chromosome segregation protein; Provisional
      cd00204
      Location:81 → 205
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:123 → 215
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:23 → 73
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:118 → 149
      ANK; ANK repeat [structural motif]
      cl03075
      Location:602 → 732
      GrpE; nucleotide exchange factor GrpE
      cl19219
      Location:589 → 662
      DUF342; Protein of unknown function (DUF342)

    5. XM_047417091.1 → XP_047273047.1  ankycorbin isoform X6

      Conserved Domains (4) summary
      PHA03095
      Location:12 → 224
      PHA03095; ankyrin-like protein; Provisional
      PRK03918
      Location:401 → 917
      PRK03918; DNA double-strand break repair ATPase Rad50
      sd00045
      Location:118 → 149
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:90 → 182
      Ank_2; Ankyrin repeats (3 copies)

    6. XM_011514017.3 → XP_011512319.1  ankycorbin isoform X2

      See identical proteins and their annotated locations for XP_011512319.1

      UniProtKB/Swiss-Prot
      E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5
      Conserved Domains (7) summary
      PRK03918
      Location:430 → 946
      PRK03918; chromosome segregation protein; Provisional
      cd00204
      Location:81 → 205
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:123 → 215
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:23 → 73
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:118 → 149
      ANK; ANK repeat [structural motif]
      cl03075
      Location:602 → 732
      GrpE; nucleotide exchange factor GrpE
      cl19219
      Location:589 → 662
      DUF342; Protein of unknown function (DUF342)

    7. XM_011514019.2 → XP_011512321.1  ankycorbin isoform X2

      See identical proteins and their annotated locations for XP_011512321.1

      UniProtKB/Swiss-Prot
      E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5
      Conserved Domains (7) summary
      PRK03918
      Location:430 → 946
      PRK03918; chromosome segregation protein; Provisional
      cd00204
      Location:81 → 205
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:123 → 215
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:23 → 73
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:118 → 149
      ANK; ANK repeat [structural motif]
      cl03075
      Location:602 → 732
      GrpE; nucleotide exchange factor GrpE
      cl19219
      Location:589 → 662
      DUF342; Protein of unknown function (DUF342)

    8. XM_011514020.2 → XP_011512322.1  ankycorbin isoform X2

      See identical proteins and their annotated locations for XP_011512322.1

      UniProtKB/Swiss-Prot
      E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5
      Conserved Domains (7) summary
      PRK03918
      Location:430 → 946
      PRK03918; chromosome segregation protein; Provisional
      cd00204
      Location:81 → 205
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:123 → 215
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:23 → 73
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:118 → 149
      ANK; ANK repeat [structural motif]
      cl03075
      Location:602 → 732
      GrpE; nucleotide exchange factor GrpE
      cl19219
      Location:589 → 662
      DUF342; Protein of unknown function (DUF342)

    9. XM_011514018.2 → XP_011512320.1  ankycorbin isoform X2

      See identical proteins and their annotated locations for XP_011512320.1

      UniProtKB/Swiss-Prot
      E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5
      Conserved Domains (7) summary
      PRK03918
      Location:430 → 946
      PRK03918; chromosome segregation protein; Provisional
      cd00204
      Location:81 → 205
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:123 → 215
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:23 → 73
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:118 → 149
      ANK; ANK repeat [structural motif]
      cl03075
      Location:602 → 732
      GrpE; nucleotide exchange factor GrpE
      cl19219
      Location:589 → 662
      DUF342; Protein of unknown function (DUF342)

    10. XM_047417089.1 → XP_047273045.1  ankycorbin isoform X2

      UniProtKB/Swiss-Prot
      E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5

    11. XM_006714469.3 → XP_006714532.1  ankycorbin isoform X2

      See identical proteins and their annotated locations for XP_006714532.1

      UniProtKB/Swiss-Prot
      E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5
      Conserved Domains (7) summary
      PRK03918
      Location:430 → 946
      PRK03918; chromosome segregation protein; Provisional
      cd00204
      Location:81 → 205
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:123 → 215
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:23 → 73
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:118 → 149
      ANK; ANK repeat [structural motif]
      cl03075
      Location:602 → 732
      GrpE; nucleotide exchange factor GrpE
      cl19219
      Location:589 → 662
      DUF342; Protein of unknown function (DUF342)

    12. XM_011514022.2 → XP_011512324.1  ankycorbin isoform X2

      See identical proteins and their annotated locations for XP_011512324.1

      UniProtKB/Swiss-Prot
      E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5
      Conserved Domains (7) summary
      PRK03918
      Location:430 → 946
      PRK03918; chromosome segregation protein; Provisional
      cd00204
      Location:81 → 205
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:123 → 215
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:23 → 73
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:118 → 149
      ANK; ANK repeat [structural motif]
      cl03075
      Location:602 → 732
      GrpE; nucleotide exchange factor GrpE
      cl19219
      Location:589 → 662
      DUF342; Protein of unknown function (DUF342)

    13. XM_047417090.1 → XP_047273046.1  ankycorbin isoform X5

    14. XM_024446017.2 → XP_024301785.1  ankycorbin isoform X3

      Conserved Domains (5) summary
      cd00204
      Location:73 → 197
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:110 → 141
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:181 → 240
      Ank_2; Ankyrin repeats (3 copies)
      pfam13857
      Location:27 → 85
      Ank_5; Ankyrin repeats (many copies)
      cl25732
      Location:422 → 938
      SMC_N; RecF/RecN/SMC N terminal domain

    15. XM_011514016.3 → XP_011512318.2  ankycorbin isoform X1

    16. XM_011514025.3 → XP_011512327.2  ankycorbin isoform X4

    17. XM_047417093.1 → XP_047273049.1  ankycorbin isoform X7

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      34903424..35079712
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054352339.1 → XP_054208314.1  ankycorbin isoform X2

      UniProtKB/Swiss-Prot
      E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5

    2. XM_054352354.1 → XP_054208329.1  ankycorbin isoform X6

    3. XM_054352352.1 → XP_054208327.1  ankycorbin isoform X6

    4. XM_054352346.1 → XP_054208321.1  ankycorbin isoform X2

      UniProtKB/Swiss-Prot
      E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5

    5. XM_054352353.1 → XP_054208328.1  ankycorbin isoform X6

    6. XM_054352340.1 → XP_054208315.1  ankycorbin isoform X2

      UniProtKB/Swiss-Prot
      E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5

    7. XM_054352345.1 → XP_054208320.1  ankycorbin isoform X2

      UniProtKB/Swiss-Prot
      E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5

    8. XM_054352344.1 → XP_054208319.1  ankycorbin isoform X2

      UniProtKB/Swiss-Prot
      E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5

    9. XM_054352343.1 → XP_054208318.1  ankycorbin isoform X2

      UniProtKB/Swiss-Prot
      E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5

    10. XM_054352341.1 → XP_054208316.1  ankycorbin isoform X2

      UniProtKB/Swiss-Prot
      E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5

    11. XM_054352347.1 → XP_054208322.1  ankycorbin isoform X2

      UniProtKB/Swiss-Prot
      E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5

    12. XM_054352342.1 → XP_054208317.1  ankycorbin isoform X2

      UniProtKB/Swiss-Prot
      E9PED3, Q6V1W9, Q7Z5I4, Q7Z733, Q9P0K7, Q9P2L2, Q9Y3T5

    13. XM_054352338.1 → XP_054208313.1  ankycorbin isoform X8

    14. XM_054352351.1 → XP_054208326.1  ankycorbin isoform X5

    15. XM_054352348.1 → XP_054208323.1  ankycorbin isoform X1

    16. XM_054352349.1 → XP_054208324.1  ankycorbin isoform X3

    17. XM_054352350.1 → XP_054208325.1  ankycorbin isoform X4

    18. XM_054352355.1 → XP_054208330.1  ankycorbin isoform X7

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9P0K7.2 GenPept UniProtKB/Swiss-Prot:Q9P0K7

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