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    rpn502 19S proteasome regulatory subunit Rpn502 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543347, updated on 18-Sep-2024

    Summary

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    Official Symbol
    rpn502
    Official Full Name
    19S proteasome regulatory subunit Rpn502
    Primary source
    PomBase:SPAPB8E5.02c
    Locus tag
    SPOM_SPAPB8E5.02C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    rpn5; rpn5-b
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    Genomic context

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    See rpn502 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (4909367..4910875, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene SMN complex subunit Yip11/Gem2 Neighboring gene ncRNA Neighboring gene rsm22-cox11 tandem protein cox1102 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene plasma membrane malate/succinate:proton symporter Mae1 Neighboring gene phosphatidylglycerol/phosphatidylinositol transfer protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Rpn5 is a conserved proteasome subunit and required for proper proteasome localization and assembly. Yen HC, et al. J Biol Chem, 2003 Aug 15. PMID 12783882
    2. Isolation of the Schizosaccharomyces pombe proteasome subunit Rpn7 and a structure-function study of the proteasome-COP9-initiation factor domain. Sha Z, et al. J Biol Chem, 2007 Nov 2. PMID 17761670, Free PMC Article
    3. Schizosaccharomyces pombe Int6 and Ras homologs regulate cell division and mitotic fidelity via the proteasome. Yen HC, et al. Cell, 2003 Jan 24. PMID 12553909
    4. Schizosaccharomyces pombe Dss1p is a DNA damage checkpoint protein that recruits Rad24p, Cdc25p, and Rae1p to DNA double-strand breaks. Selvanathan SP, et al. J Biol Chem, 2010 May 7. PMID 20231270, Free PMC Article
    5. Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution. Bohn S, et al. Proc Natl Acad Sci U S A, 2010 Dec 7. PMID 21098295, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nuclear periphery IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of proteasome complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of proteasome regulatory particle, lid subcomplex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of proteasome regulatory particle, lid subcomplex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    19S proteasome regulatory subunit Rpn502

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4909367..4910875 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020204.3 → NP_594776.1  19S proteasome regulatory subunit Rpn502 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594776.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14381, P0CU17, P0CU18, Q9UTM3
      Conserved Domains (1) summary
      COG5071
      Location:1 → 438
      RPN5; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]
    Nucleotide Protein
    Heading Accession and Version

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