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    sar1 ADP-ribosylation factor Sar1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540439, updated on 17-May-2024

    Summary

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    Gene symbol
    sar1
    Gene description
    ADP-ribosylation factor Sar1
    Primary source
    PomBase:SPBC31F10.06c
    Locus tag
    SPBC31F10.06c
    See related
    FungiDB:SPBC31F10.06c; VEuPathDB:SPBC31F10.06c
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See sar1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003423.3 (3760610..3761884, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene putative acyl-CoA thioesterase Neighboring gene putative ChaC-like cation transport regulator Neighboring gene mediator complex subunit Srb4 Neighboring gene protein mug37 Neighboring gene putative protein lsb5 Neighboring gene mediator complex subunit Med10 Neighboring gene protein Mde2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fission yeast and a plant have functional homologues of the Sar1 and Sec12 proteins involved in ER to Golgi traffic in budding yeast. d'Enfert C, et al. EMBO J, 1992 Nov. PMID 1396601, Free PMC Article
    2. Three proteins required for early steps in the protein secretory pathway also affect nuclear envelope structure and cell cycle progression in fission yeast. Matynia A, et al. J Cell Sci, 2002 Jan 15. PMID 11839792
    3. The fission yeast spo14+ gene encoding a functional homologue of budding yeast Sec12 is required for the development of forespore membranes. Nakamura-Kubo M, et al. Mol Biol Cell, 2003 Mar. PMID 12631727, Free PMC Article
    4. Mis17 is a regulatory module of the Mis6-Mal2-Sim4 centromere complex that is required for the recruitment of CenH3/CENP-A in fission yeast. Shiroiwa Y, et al. PLoS One, 2011 Mar 21. PMID 21445296, Free PMC Article
    5. The SH3 domains of two PCH family members cooperate in assembly of the Schizosaccharomyces pombe contractile ring. Roberts-Galbraith RH, et al. J Cell Biol, 2009 Jan 12. PMID 19139265, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables GTP binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum membrane organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in membrane organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of protein exit from endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of COPII vesicle coating IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in vesicle organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of COPII vesicle coat IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm HDA PubMed 
    is_active_in endoplasmic reticulum HDA PubMed 
    is_active_in endoplasmic reticulum exit site IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ADP-ribosylation factor Sar1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3760610..3761884 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022489.2 → NP_596568.1  ADP-ribosylation factor Sar1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596568.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q01475
      Conserved Domains (2) summary
      smart00178
      Location:4 → 190
      SAR; Sar1p-like members of the Ras-family of small GTPases
      cd00879
      Location:2 → 190
      Sar1; Sar1 is an essential component of COPII vesicle coats
    Nucleotide Protein
    Heading Accession and Version

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