Gm4787 predicted gene 4787 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Gm4787provided by MGI
Official Full Name: predicted gene 4787provided by MGI
Primary source: MGI:MGI:3646380
See related: Ensembl:ENSMUSG00000072974 AllianceGenome:MGI:3646380
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Adam4b; EG214321
Summary: Predicted to enable metalloendopeptidase activity. Predicted to be involved in male gonad development and proteolysis. Predicted to be active in external side of plasma membrane and sperm head plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: 12 D1; 12 37.62 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	12	NC_000078.7 (81423765..81426260, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	12	NC_000078.6 (81376991..81379486, complement)

Chromosome 12 - NC_000078.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables metalloendopeptidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in male gonad development	IBA Inferred from Biological aspect of Ancestor more info
involved_in proteolysis	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in external side of plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in sperm head plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: a disintegrin and metalloprotease domain 4b

Names: a disintegrin and metallopeptidase domain 4b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001038995.2 → NP_001034084.2 a disintegrin and metalloprotease domain 4b precursor

See identical proteins and their annotated locations for NP_001034084.2

Status: VALIDATED

Source sequence(s)

AC132391, BQ129905, CJ047802

Consensus CDS

CCDS26018.1

UniProtKB/TrEMBL

B2RUD9, Q6IMH8

Related

ENSMUSP00000077390.6, ENSMUST00000062182.8

Conserved Domains (4) summary

smart00608
Location:501 → 642

ACR; ADAM Cysteine-Rich Domain

cd04269
Location:213 → 405

ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...

pfam00200
Location:425 → 498

Disintegrin; Disintegrin

pfam01562
Location:60 → 163

Pep_M12B_propep; Reprolysin family propeptide