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    Bend7 BEN domain containing 7 [ Mus musculus (house mouse) ]

    Gene ID: 209645, updated on 28-Oct-2024

    Summary

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    Official Symbol
    Bend7provided by MGI
    Official Full Name
    BEN domain containing 7provided by MGI
    Primary source
    MGI:MGI:2443100
    See related
    Ensembl:ENSMUSG00000048186 AllianceGenome:MGI:2443100
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1110017O21Rik; E130319B15Rik
    Summary
    Predicted to enable DNA binding activity. Is expressed in ductus deferens; metanephros; prostate gland; and testis. Orthologous to human BEND7 (BEN domain containing 7). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Broad expression in large intestine adult (RPKM 5.2), lung adult (RPKM 3.5) and 23 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Bend7 in Genome Data Viewer
    Location:
    2 A1; 2 2.88 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (4722593..4807035)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (4717787..4802224)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_03542 Neighboring gene pre-mRNA processing factor 18 Neighboring gene STARR-seq mESC enhancer starr_03543 Neighboring gene STARR-seq mESC enhancer starr_03544 Neighboring gene ribosomal protein L22 pseudogene Neighboring gene predicted gene, 36389 Neighboring gene protein regulator of cytokinesis 1 pseudogene Neighboring gene selenophosphate synthetase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    2. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    BEN domain-containing protein 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001190400.1 → NP_001177329.1  BEN domain-containing protein 7 isoform 2

      See identical proteins and their annotated locations for NP_001177329.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
      Source sequence(s)
      AK053896, AL807778, AL928550
      Consensus CDS
      CCDS70974.1
      UniProtKB/TrEMBL
      B7ZMX8
      Related
      ENSMUSP00000139220.2, ENSMUST00000184139.8
      Conserved Domains (1) summary
      pfam10523
      Location:312 → 391
      BEN; BEN domain

    2. NM_178663.4 → NP_848778.1  BEN domain-containing protein 7 isoform 1

      See identical proteins and their annotated locations for NP_848778.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK030428, AL807778, AL928550
      Consensus CDS
      CCDS15658.1
      UniProtKB/Swiss-Prot
      Q4VAD9, Q6PHN3, Q8BPJ4, Q8BSV3, Q8C973
      UniProtKB/TrEMBL
      B7ZMX8, Q0VE44
      Related
      ENSMUSP00000052458.7, ENSMUST00000056914.7
      Conserved Domains (1) summary
      pfam10523
      Location:312 → 391
      BEN; BEN domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      4722593..4807035
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036160210.1 → XP_036016103.1  BEN domain-containing protein 7 isoform X1

      UniProtKB/TrEMBL
      B7ZMX8
      Conserved Domains (1) summary
      pfam10523
      Location:284 → 365
      BEN; BEN domain

    2. XM_036160211.1 → XP_036016104.1  BEN domain-containing protein 7 isoform X2

      UniProtKB/TrEMBL
      B7ZMX8
      Conserved Domains (1) summary
      pfam10523
      Location:284 → 365
      BEN; BEN domain

    3. XM_006497445.3 → XP_006497508.1  BEN domain-containing protein 7 isoform X3

      See identical proteins and their annotated locations for XP_006497508.1

      UniProtKB/TrEMBL
      B7ZMX8
      Conserved Domains (1) summary
      smart01025
      Location:259 → 343
      BEN; The BEN domain is found in diverse animal proteins

    RNA

    1. XR_004939300.1 RNA Sequence

    2. XR_004939303.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BSV3.1 GenPept UniProtKB/Swiss-Prot:Q8BSV3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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