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    pyrD dihydroorotate dehydrogenase PyrD [ Sulfolobus islandicus LAL14/1 ]

    Gene ID: 15297910, updated on 7-Jun-2023

    Summary

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    Gene symbol
    pyrD
    Gene description
    dihydroorotate dehydrogenase PyrD
    Locus tag
    SIL_RS07025
    Gene type
    protein coding
    Organism
    Sulfolobus islandicus LAL14/1 (strain: LAL14/1)
    Lineage
    Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae; Sulfolobus
    Old locus tag
    SiL_1400
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    Genomic context

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    Sequence:
    NC_021058.1 (1306227..1307099)

    NC_021058.1Genomic Context describing neighboring genes Neighboring gene aspartate carbamoyltransferase Neighboring gene 2-polyprenylphenol hydroxylase Neighboring gene aspartate carbamoyltransferase regulatory subunit Neighboring gene dihydroorotase Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene MarC family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_021058.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genes of de novo pyrimidine biosynthesis from the hyperthermoacidophilic crenarchaeote Sulfolobus acidocaldarius: novel organization in a bipolar operon. Thia-Toong TL, et al. J Bacteriol, 2002 Aug. PMID 12142413, Free PMC Article
    2. Genomics and genetics of Sulfolobus islandicus LAL14/1, a model hyperthermophilic archaeon. Jaubert C, et al. Open Biol, 2013 Apr 17. PMID 23594878, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    dihydroorotate dehydrogenase PyrD
    WP_012711516.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_021058.1 Reference assembly

      Range
      1306227..1307099
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_012711516.1 dihydroorotate dehydrogenase PyrD [Sulfolobus islandicus]

      See identical proteins and their annotated locations for WP_012711516.1

      UniProtKB/TrEMBL
      C3MW49, F0NI99, F0NPS9, M9U9S6
      Conserved Domains (2) summary
      TIGR01037
      Location:2 → 287
      pyrD_sub1_fam; dihydroorotate dehydrogenase (subfamily 1) family protein
      cd04740
      Location:1 → 287
      DHOD_1B_like; Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine ...
    Nucleotide Protein
    Heading Accession and Version