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    mt-cyb cytochrome b, mitochondrial [ Danio rerio (zebrafish) ]

    Gene ID: 140512, updated on 18-Sep-2024

    Summary

    Official Symbol
    mt-cybprovided by ZNC
    Official Full Name
    cytochrome b, mitochondrialprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-011205-17
    See related
    AllianceGenome:ZFIN:ZDB-GENE-011205-17
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    mtcyb; CYTB
    Summary
    Predicted to enable metal ion binding activity and ubiquinol-cytochrome-c reductase activity. Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to act upstream of or within respiratory electron transport chain. Predicted to be located in mitochondrial inner membrane and respirasome. Predicted to be integral component of membrane. Predicted to be part of mitochondrial respiratory chain complex III. Predicted to be intrinsic component of membrane. Is expressed in brain and male organism. Human ortholog(s) of this gene implicated in ovarian carcinoma and urinary bladder cancer. Orthologous to human MT-CYB (mitochondrially encoded cytochrome b). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See mt-cyb in Genome Data Viewer
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) MT (non-nuclear) NC_002333.2 (15308..16448)
    105 previous assembly GRCz10 (GCF_000002035.5) MT (non-nuclear) NC_002333.2 (15308..16448)

    Chromosome MT - NC_002333.2Genomic Context describing neighboring genes Neighboring gene NADH dehydrogenase subunit 5 Neighboring gene NADH dehydrogenase subunit 6 Neighboring gene tRNA-Glu Neighboring gene tRNA-Thr Neighboring gene tRNA-Pro

    Genomic regions, transcripts, and products

    Pathways from PubChem

    General gene information

    Markers

    • COB; Cytb

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables electron transfer activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to ubiquinol-cytochrome-c reductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ubiquinol-cytochrome-c reductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, ubiquinol to cytochrome c IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within respiratory electron transport chain IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    part_of respiratory chain complex III IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of respiratory chain complex III IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    cytochrome b
    NP_059343.1
    • TAA stop codon is completed by the addition of 3' A residues to the mRNA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002333.2 Reference assembly

      Range
      15308..16448
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_059343.1 cytochrome b (mitochondrion) [Danio rerio]

      See identical proteins and their annotated locations for NP_059343.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9MIX8, Q9TA52
      UniProtKB/TrEMBL
      A0A0A0VDB5
      Conserved Domains (3) summary
      MTH00131
      Location:1380
      CYTB; cytochrome b; Provisional
      cd00284
      Location:9206
      Cytochrome_b_N; Cytochrome b (N-terminus)/b6/petB: Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria, ...
      cd00290
      Location:207354
      cytochrome_b_C; Cytochrome b(C-terminus)/b6/petD: Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria, ...