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    FXN frataxin [ Panthera uncia (snow leopard) ]

    Gene ID: 125924760, updated on 22-Mar-2024

    Summary

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    Gene symbol
    FXN
    Gene description
    frataxin
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Panthera uncia
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae; Panthera
    Orthologs
    human mouse all
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    Genomic context

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    See FXN in Genome Data Viewer
    Location:
    chromosome: D4
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2023_02 current Puncia_PCG_1.0 (GCF_023721935.1) D4 NC_064807.1 (11541324..11565120)

    Chromosome D4 - NC_064807.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC125924788 Neighboring gene phosphatidylinositol-4-phosphate 5-kinase type 1 beta Neighboring gene PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 Neighboring gene tight junction protein 2 Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1-like Neighboring gene endosomal transmembrane epsin interactor 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_064807.1 Chromosome D4 Reference Puncia_PCG_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 2 iron, 2 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ferric iron binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ferrous iron binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ferroxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables iron chaperone activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular iron ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in iron incorporation into metallo-sulfur cluster IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    frataxin, mitochondrial

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_023721935.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Puncia_PCG_1.0 Primary Assembly

    Genomic

    1. NC_064807.1 Reference Puncia_PCG_1.0 Primary Assembly

      Range
      11541324..11565120
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_049633531.1 → XP_049489488.1  frataxin, mitochondrial

    Nucleotide Protein
    Heading Accession and Version

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