U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    ygiY putative sensory histidine kinase in regulatory system [ Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 ]

    Gene ID: 1254701, updated on 6-Oct-2023

    Summary

    Go to the top of the page Help
    Gene symbol
    ygiY
    Gene description
    putative sensory histidine kinase in regulatory system
    Locus tag
    STM3178
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 (strain: LT2, serovar: Typhimurium, sub-species: enterica, culture-collection: ATCC:700720, culture-collection: SGSC:1412, type-material: type strain of Salmonella enterica)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Salmonella
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_003197.2 (3341450..3342810)

    NC_003197.2Genomic Context describing neighboring genes Neighboring gene putative bacterial regulatory helix-turn-helix protein Neighboring gene putative outer membrane protein Neighboring gene putative transcriptional regulator Neighboring gene NADPH specific quinone oxidoreductase Neighboring gene putative cytoplasmic protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003197.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Pyroptosis of Salmonella Typhimurium-infected macrophages was suppressed and elimination of intracellular bacteria from macrophages was promoted by blocking QseC. Li Z, et al. Sci Rep, 2016 Nov 17. PMID 27853287, Free PMC Article
    2. QseC mediates Salmonella enterica serovar typhimurium virulence in vitro and in vivo. Moreira CG, et al. Infect Immun, 2010 Mar. PMID 20028809, Free PMC Article
    3. Norepinephrine augments Salmonella enterica-induced enteritis in a manner associated with increased net replication but independent of the putative adrenergic sensor kinases QseC and QseE. Pullinger GD, et al. Infect Immun, 2010 Jan. PMID 19884332, Free PMC Article
    4. The role of the QseC quorum-sensing sensor kinase in colonization and norepinephrine-enhanced motility of Salmonella enterica serovar Typhimurium. Bearson BL, et al. Microb Pathog, 2008 Apr. PMID 17997077
    5. Complete genome sequence of Salmonella enterica serovar Typhimurium LT2. McClelland M, et al. Nature, 2001 Oct 25. PMID 11677609

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. QseC is a virulence factor in Salmonella typhimurium.
      Title: Pyroptosis of Salmonella Typhimurium-infected macrophages was suppressed and elimination of intracellular bacteria from macrophages was promoted by blocking QseC.
    2. A qseC mutant was impaired in flagellar motility, in invasion of epithelial cells, and in survival within macrophages and was attenuated for systemic infection in 129x1/SvJ mice.
      Title: QseC mediates Salmonella enterica serovar typhimurium virulence in vitro and in vivo.
    3. The adrenergic sensors QseC and QseE were not required for norepinephrine (NE)-enhanced enteritis, intestinal colonization of calves, or NE-dependent growth in culture media and did not influence virulence factors.
      Title: Norepinephrine augments Salmonella enterica-induced enteritis in a manner associated with increased net replication but independent of the putative adrenergic sensor kinases QseC and QseE.
    4. This study has identified a role for the QseBC quorum-sensing signal transduction system in motility and swine colonization of S. Typhimurium.
      Title: The role of the QseC quorum-sensing sensor kinase in colonization and norepinephrine-enhanced motility of Salmonella enterica serovar Typhimurium.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    regulatory

    • Loc: 3341450-3341455 regulatory_class = ribosome_binding_site

    General protein information

    Go to the top of the page Help
    Preferred Names
    putative sensory histidine kinase in regulatory system
    NP_462093.1
    • similar to E. coli putative 2-component sensor protein (AAC76062.1); Blastp hit to AAC76062.1 (449 aa), 79% identity in aa 1 - 449

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003197.2 Reference assembly

      Range
      3341450..3342810
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_462093.1 putative sensory histidine kinase in regulatory system [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]

      See identical proteins and their annotated locations for NP_462093.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A3V9E2Y9, A0A5T7I6H9, A0A5U1VPZ9, A0A5Y7TGW2, A0A631TR70, A0A704XAD3, A0A705YVQ8, A0A723NGZ0, A0A757UK37, A0A762MUW0
      Conserved Domains (1) summary
      PRK10337
      Location:1 → 449
      PRK10337; sensor protein QseC; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8ZLZ9.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials