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    PLEC plectin [ Geotrypetes seraphini ]

    Gene ID: 117356037, updated on 19-Mar-2024

    Summary

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    Gene symbol
    PLEC
    Gene description
    plectin
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Geotrypetes seraphini
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Gymnophiona; Geotrypetes
    Orthologs
    human mouse all
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    Genomic context

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    See PLEC in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    71
    Annotation release Status Assembly Chr Location
    100 current aGeoSer1.1 (GCF_902459505.1) 2 NC_047085.1 (8157787..8681675, complement)

    Chromosome 2 - NC_047085.1Genomic Context describing neighboring genes Neighboring gene nuclear receptor binding protein 2 Neighboring gene epiplakin-like Neighboring gene alanine aminotransferase 2-like Neighboring gene alanine aminotransferase 2-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_047085.1 Chromosome 2 Reference aGeoSer1.1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ankyrin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cadherin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables structural constituent of cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables structural constituent of muscle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in hemidesmosome assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intermediate filament cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in wound healing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in hemidesmosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in intermediate filament IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in sarcolemma IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LOW QUALITY PROTEIN: plectin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Geotrypetes seraphini Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference aGeoSer1.1 Primary Assembly

    Genomic

    1. NC_047085.1 Reference aGeoSer1.1 Primary Assembly

      Range
      8157787..8681675 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_033935291.1 → XP_033791182.1  LOW QUALITY PROTEIN: plectin

      UniProtKB/TrEMBL
      A0A6P8PSF6
      Conserved Domains (13) summary
      PTZ00121
      Location:2342 → 3186
      PTZ00121; MAEBL; Provisional
      smart00250
      Location:4039 → 4070
      PLEC; Plectin repeat
      COG1196
      Location:1502 → 2217
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00051
      Location:6878 → 6940
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd00176
      Location:6385 → 6602
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      pfam00681
      Location:4654 → 4693
      Plectin; Plectin repeat
      pfam02187
      Location:6955 → 7023
      GAS2; Growth-Arrest-Specific Protein 2 Domain
      pfam03501
      Location:7 → 99
      S10_plectin; Plectin/S10 domain
      pfam17902
      Location:1396 → 1461
      SH3_10; SH3 domain
      pfam18373
      Location:1496 → 1573
      Spectrin_like; Spectrin like domain
      cd21188
      Location:647 → 751
      CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
      NF033930
      Location:3113 → 3310
      pneumo_PspA; pneumococcal surface protein A
      cl00030
      Location:764 → 869
      CH_SF; calponin homology (CH) domain superfamily
    Nucleotide Protein
    Heading Accession and Version

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