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    DLG1 discs large MAGUK scaffold protein 1 [ Strigops habroptila (Kakapo) ]

    Gene ID: 115611598, updated on 3-Aug-2024

    Summary

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    Gene symbol
    DLG1
    Gene description
    discs large MAGUK scaffold protein 1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Strigops habroptila
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Psittaciformes; Psittacidae; Strigops
    Orthologs
    human mouse all
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    Genomic context

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    See DLG1 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    101 current bStrHab1.2.pri (GCF_004027225.2) 8 NC_044284.2 (23162295..23322748, complement)
    100 previous assembly bStrHab1_v1.p (GCF_004027225.1) 8 NC_044284.1 (23162295..23322728, complement)

    Chromosome 8 - NC_044284.2Genomic Context describing neighboring genes Neighboring gene NCBP2 antisense 2 (head to head) Neighboring gene phosphatidylinositol glycan anchor biosynthesis class Z Neighboring gene melanotransferrin Neighboring gene 3-hydroxybutyrate dehydrogenase 1 Neighboring gene apolipoprotein D

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neurotransmitter receptor localization to postsynaptic specialization membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuromuscular junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    disks large homolog 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Strigops habroptila Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bStrHab1.2.pri

    Genomic

    1. NC_044284.2 Reference bStrHab1.2.pri

      Range
      23162295..23322748 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030494769.2 → XP_030350629.1  disks large homolog 1 isoform X10

      UniProtKB/TrEMBL
      A0A672VB89
      Conserved Domains (7) summary
      cd12031
      Location:584 → 650
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:465 → 549
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:714 → 892
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:2 → 62
      L27_1
      pfam10600
      Location:404 → 467
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    2. XM_030494767.2 → XP_030350627.1  disks large homolog 1 isoform X8

      UniProtKB/TrEMBL
      A0A672VB89
      Conserved Domains (7) summary
      cd12031
      Location:584 → 650
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:465 → 549
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:716 → 894
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:2 → 62
      L27_1
      pfam10600
      Location:404 → 467
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    3. XM_030494762.2 → XP_030350622.1  disks large homolog 1 isoform X4

      UniProtKB/TrEMBL
      A0A672VBB9
      Conserved Domains (7) summary
      cd12031
      Location:584 → 650
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:465 → 549
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:737 → 915
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:2 → 62
      L27_1
      pfam10600
      Location:404 → 467
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    4. XM_030494760.2 → XP_030350620.1  disks large homolog 1 isoform X2

      UniProtKB/TrEMBL
      A0A672VBB9
      Conserved Domains (7) summary
      cd12031
      Location:584 → 650
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:465 → 549
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:738 → 916
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:2 → 62
      L27_1
      pfam10600
      Location:404 → 467
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    5. XM_032920112.1 → XP_032776003.1  disks large homolog 1 isoform X20

      UniProtKB/TrEMBL
      A0A672VBB9
      Conserved Domains (7) summary
      cd12031
      Location:584 → 650
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:465 → 549
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:750 → 928
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:2 → 62
      L27_1
      pfam10600
      Location:404 → 467
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    6. XM_030494773.2 → XP_030350633.1  disks large homolog 1 isoform X14

      UniProtKB/TrEMBL
      A0A672VB89
      Conserved Domains (7) summary
      cd12031
      Location:585 → 651
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:466 → 550
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:703 → 881
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:2 → 62
      L27_1
      pfam10600
      Location:405 → 468
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    7. XM_030494768.2 → XP_030350628.1  disks large homolog 1 isoform X9

      UniProtKB/TrEMBL
      A0A672VB89
      Conserved Domains (7) summary
      cd12031
      Location:585 → 651
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:466 → 550
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:715 → 893
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:2 → 62
      L27_1
      pfam10600
      Location:405 → 468
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    8. XM_030494766.2 → XP_030350626.1  disks large homolog 1 isoform X7

      UniProtKB/TrEMBL
      A0A672VB89
      Conserved Domains (7) summary
      cd12031
      Location:585 → 651
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:466 → 550
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:717 → 895
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:2 → 62
      L27_1
      pfam10600
      Location:405 → 468
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    9. XM_030494764.2 → XP_030350624.1  disks large homolog 1 isoform X6

      UniProtKB/TrEMBL
      A0A672VBB9
      Conserved Domains (7) summary
      cd12031
      Location:585 → 651
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:466 → 550
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:724 → 902
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:2 → 62
      L27_1
      pfam10600
      Location:405 → 468
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    10. XM_030494761.2 → XP_030350621.1  disks large homolog 1 isoform X3

      UniProtKB/TrEMBL
      A0A672VBB9
      Conserved Domains (7) summary
      cd12031
      Location:585 → 651
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:466 → 550
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:738 → 916
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:2 → 62
      L27_1
      pfam10600
      Location:405 → 468
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    11. XM_030494763.2 → XP_030350623.1  disks large homolog 1 isoform X5

      UniProtKB/TrEMBL
      A0A672VBB9
      Conserved Domains (7) summary
      cd12031
      Location:585 → 651
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:466 → 550
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:725 → 903
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:2 → 62
      L27_1
      pfam10600
      Location:405 → 468
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    12. XM_030494759.2 → XP_030350619.1  disks large homolog 1 isoform X1

      UniProtKB/TrEMBL
      A0A672VBB9
      Conserved Domains (7) summary
      cd12031
      Location:585 → 651
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:466 → 550
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:739 → 917
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:2 → 62
      L27_1
      pfam10600
      Location:405 → 468
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    13. XM_030494778.1 → XP_030350638.1  disks large homolog 1 isoform X18

      UniProtKB/TrEMBL
      A0A672V8J9
      Conserved Domains (7) summary
      cd12031
      Location:372 → 438
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:253 → 337
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      pfam00625
      Location:526 → 704
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:2 → 62
      L27_1
      pfam10600
      Location:192 → 255
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 168
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
      cl00117
      Location:160 → 191
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

    14. XM_030494774.1 → XP_030350634.1  disks large homolog 1 isoform X15

      UniProtKB/TrEMBL
      A0A672V7M3
      Conserved Domains (7) summary
      cd12031
      Location:551 → 617
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:432 → 516
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:191 → 275
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:683 → 861
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:2 → 62
      L27_1
      pfam10600
      Location:371 → 434
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 190
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    15. XM_030494781.1 → XP_030350641.1  disks large homolog 1 isoform X22

      UniProtKB/TrEMBL
      A0A672V7M3
      Conserved Domains (7) summary
      cd12031
      Location:551 → 617
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:432 → 516
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:191 → 275
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:695 → 873
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:2 → 62
      L27_1
      pfam10600
      Location:371 → 434
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 190
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    16. XM_030494784.1 → XP_030350644.1  disks large homolog 1 isoform X25

      UniProtKB/TrEMBL
      A0A672V7M3
      Conserved Domains (7) summary
      cd12031
      Location:551 → 617
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:432 → 516
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:191 → 275
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:690 → 868
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:2 → 62
      L27_1
      pfam10600
      Location:371 → 434
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 190
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    17. XM_030494772.1 → XP_030350632.1  disks large homolog 1 isoform X13

      UniProtKB/TrEMBL
      A0A672V7M3
      Conserved Domains (7) summary
      cd12031
      Location:551 → 617
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:432 → 516
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:191 → 275
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:704 → 882
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:2 → 62
      L27_1
      pfam10600
      Location:371 → 434
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 190
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    18. XM_030494771.1 → XP_030350631.1  disks large homolog 1 isoform X12

      UniProtKB/TrEMBL
      A0A672V7M3
      Conserved Domains (7) summary
      cd12031
      Location:551 → 617
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:432 → 516
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:191 → 275
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:705 → 883
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:2 → 62
      L27_1
      pfam10600
      Location:371 → 434
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 190
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    19. XM_030494770.1 → XP_030350630.1  disks large homolog 1 isoform X11

      UniProtKB/TrEMBL
      A0A672V7M3
      Conserved Domains (7) summary
      cd12031
      Location:552 → 618
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:433 → 517
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:191 → 275
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:706 → 884
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:2 → 62
      L27_1
      pfam10600
      Location:372 → 435
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 190
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    20. XM_030494780.1 → XP_030350640.1  disks large homolog 1 isoform X21

      UniProtKB/TrEMBL
      A0A672VB97
      Conserved Domains (6) summary
      cd12031
      Location:542 → 608
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:423 → 507
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:182 → 266
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:696 → 874
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:362 → 425
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:64 → 181
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    21. XM_030494782.1 → XP_030350642.1  disks large homolog 1 isoform X23

      UniProtKB/TrEMBL
      A0A672V8L5
      Conserved Domains (6) summary
      cd12031
      Location:498 → 564
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:379 → 463
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:138 → 222
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:630 → 808
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:318 → 381
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:107 → 137
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    22. XM_030494783.1 → XP_030350643.1  disks large homolog 1 isoform X24

      UniProtKB/TrEMBL
      A0A672V8L5
      Conserved Domains (6) summary
      cd12031
      Location:498 → 564
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:379 → 463
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:138 → 222
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:642 → 820
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:318 → 381
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:107 → 137
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    23. XM_030494775.1 → XP_030350635.1  disks large homolog 1 isoform X16

      UniProtKB/TrEMBL
      A0A672V8L5
      Conserved Domains (6) summary
      cd12031
      Location:525 → 591
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:406 → 490
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:164 → 248
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:679 → 857
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:345 → 408
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:50 → 163
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

    24. XM_030494779.1 → XP_030350639.1  disks large homolog 1 isoform X19

      Conserved Domains (5) summary
      cd12031
      Location:330 → 396
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:211 → 295
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:62 → 149
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:484 → 662
      Guanylate_kin; Guanylate kinase
      pfam10600
      Location:150 → 213
      PDZ_assoc; PDZ-associated domain of NMDA receptors

    25. XM_030494777.2 → XP_030350637.1  disks large homolog 1 isoform X17

      UniProtKB/TrEMBL
      A0A672VBB9
      Conserved Domains (7) summary
      cd12031
      Location:585 → 651
      SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
      smart00228
      Location:466 → 550
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:224 → 308
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00625
      Location:739 → 829
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:2 → 62
      L27_1
      pfam10600
      Location:405 → 468
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:106 → 223
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
    Nucleotide Protein
    Heading Accession and Version

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