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    sh2d3ca SH2 domain containing 3Ca [ Gadus morhua (Atlantic cod) ]

    Gene ID: 115541592, updated on 17-Mar-2024

    Summary

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    Gene symbol
    sh2d3ca
    Gene description
    SH2 domain containing 3Ca
    See related
    Ensembl:ENSGMOG00000006010
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gadus morhua
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Zeiogadaria; Gadariae; Gadiformes; Gadoidei; Gadidae; Gadus
    Orthologs
    zebrafish all
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    Genomic context

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    See sh2d3ca in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    100 current gadMor3.0 (GCF_902167405.1) 4 NC_044051.1 (15726294..15778379, complement)

    Chromosome 4 - NC_044051.1Genomic Context describing neighboring genes Neighboring gene cerebral endothelial cell adhesion molecule Neighboring gene ubiquitin related modifier 1 Neighboring gene spermatid perinuclear RNA binding protein Neighboring gene uncharacterized LOC115541539

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_044051.1 Chromosome 4 Reference gadMor3.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphotyrosine residue binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in small GTPase-mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SH2 domain-containing protein 3C-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gadus morhua Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference gadMor3.0 Primary Assembly

    Genomic

    1. NC_044051.1 Reference gadMor3.0 Primary Assembly

      Range
      15726294..15778379 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030353377.1 → XP_030209237.1  SH2 domain-containing protein 3C-like isoform X2

      Conserved Domains (2) summary
      cd10337
      Location:263 → 398
      SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
      cl02485
      Location:630 → 900
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

    2. XM_030353376.1 → XP_030209236.1  SH2 domain-containing protein 3C-like isoform X1

      Conserved Domains (2) summary
      cd10337
      Location:263 → 398
      SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
      cl02485
      Location:656 → 926
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

    3. XM_030353378.1 → XP_030209238.1  SH2 domain-containing protein 3C-like isoform X3

      Conserved Domains (2) summary
      cd10337
      Location:230 → 365
      SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
      cl02485
      Location:623 → 893
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

    4. XM_030353379.1 → XP_030209239.1  SH2 domain-containing protein 3C-like isoform X4

      UniProtKB/TrEMBL
      A0A8C4Z4Z9
      Conserved Domains (3) summary
      cd10337
      Location:60 → 195
      SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
      pfam15800
      Location:186 → 327
      CiPC; Clock interacting protein circadian
      cl02485
      Location:453 → 723
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

    5. XM_030353380.1 → XP_030209240.1  SH2 domain-containing protein 3C-like isoform X5

      UniProtKB/TrEMBL
      A0A8C4Z4Z9
      Related
      ENSGMOP00000006388.2, ENSGMOT00000006574.2
      Conserved Domains (3) summary
      cd10337
      Location:55 → 190
      SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
      pfam15800
      Location:181 → 322
      CiPC; Clock interacting protein circadian
      cl02485
      Location:448 → 718
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
    Nucleotide Protein
    Heading Accession and Version

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