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    pleca plectin a [ Betta splendens (Siamese fighting fish) ]

    Gene ID: 114865412, updated on 20-Aug-2024

    Summary

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    Gene symbol
    pleca
    Gene description
    plectin a
    See related
    EnsemblRapid:ENSBSLG00000011095
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Betta splendens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Anabantaria; Anabantiformes; Anabantoidei; Osphronemidae; Betta
    Orthologs
    zebrafish all
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    Genomic context

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    See pleca in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    48
    Annotation release Status Assembly Chr Location
    RS_2023_04 current fBetSpl5.4 (GCF_900634795.4) 11 NC_040891.2 (13655514..13716440, complement)
    101 previous assembly fBetSpl5.3 (GCF_900634795.3) 11 NC_040891.1 (13764456..13825117, complement)

    Chromosome 11 - NC_040891.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114865422 Neighboring gene uncharacterized LOC114865419 Neighboring gene doublesex- and mab-3-related transcription factor 1-like Neighboring gene uncharacterized LOC114865420 Neighboring gene eukaryotic translation initiation factor 3, subunit E, b Neighboring gene transmembrane protein 74

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ankyrin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cadherin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables structural constituent of cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables structural constituent of muscle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in hemidesmosome assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intermediate filament cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in wound healing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in hemidesmosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in intermediate filament IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in sarcolemma IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    plectin a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_900634795.4-RS_2023_04

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference fBetSpl5.4 Primary Assembly

    Genomic

    1. NC_040891.2 Reference fBetSpl5.4 Primary Assembly

      Range
      13655514..13716440 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_029166520.3 → XP_029022353.1  plectin a isoform X2

      UniProtKB/TrEMBL
      A0A6P7NWK3
      Conserved Domains (8) summary
      PTZ00121
      Location:1952 → 2821
      PTZ00121; MAEBL; Provisional
      smart00150
      Location:698 → 791
      SPEC; Spectrin repeats
      smart00250
      Location:2956 → 2990
      PLEC; Plectin repeat
      COG5069
      Location:195 → 429
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:793 → 983
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      pfam00681
      Location:4226 → 4265
      Plectin; Plectin repeat
      pfam15921
      Location:1178 → 1859
      CCDC158; Coiled-coil domain-containing protein 158
      cl27652
      Location:3575 → 3614
      Plectin; Plectin repeat

    2. XM_055512834.1 → XP_055368809.1  plectin a isoform X8

      UniProtKB/TrEMBL
      A0A9W2Y4E5

    3. XM_055512833.1 → XP_055368808.1  plectin a isoform X7

      UniProtKB/TrEMBL
      A0A9W2Y449

    4. XM_055512831.1 → XP_055368806.1  plectin a isoform X4

      UniProtKB/TrEMBL
      A0A9W2Y3V5

    5. XM_055512832.1 → XP_055368807.1  plectin a isoform X5

      UniProtKB/TrEMBL
      A0A9W2Y4B3

    6. XM_055512830.1 → XP_055368805.1  plectin a isoform X3

      UniProtKB/TrEMBL
      A0A9W2Y4M3

    7. XM_055512829.1 → XP_055368804.1  plectin a isoform X1

      UniProtKB/TrEMBL
      A0A9W2Y481

    8. XM_029166525.3 → XP_029022358.1  plectin a isoform X9

      UniProtKB/TrEMBL
      A0A6P7NWK8
      Conserved Domains (8) summary
      PTZ00121
      Location:1925 → 2794
      PTZ00121; MAEBL; Provisional
      smart00150
      Location:686 → 779
      SPEC; Spectrin repeats
      smart00250
      Location:2929 → 2963
      PLEC; Plectin repeat
      COG5069
      Location:195 → 417
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:781 → 971
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      pfam00681
      Location:4199 → 4238
      Plectin; Plectin repeat
      pfam15921
      Location:1151 → 1832
      CCDC158; Coiled-coil domain-containing protein 158
      cl27652
      Location:3548 → 3587
      Plectin; Plectin repeat

    9. XM_029166522.3 → XP_029022355.1  plectin a isoform X6

      UniProtKB/TrEMBL
      A0A6P7NWJ1
      Related
      ENSBSLP00000032786.3, ENSBSLT00000036280.3
      Conserved Domains (8) summary
      PTZ00121
      Location:1940 → 2809
      PTZ00121; MAEBL; Provisional
      smart00150
      Location:686 → 779
      SPEC; Spectrin repeats
      smart00250
      Location:2944 → 2978
      PLEC; Plectin repeat
      COG5069
      Location:195 → 417
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:781 → 971
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      pfam00681
      Location:4214 → 4253
      Plectin; Plectin repeat
      pfam15921
      Location:1166 → 1847
      CCDC158; Coiled-coil domain-containing protein 158
      cl27652
      Location:3563 → 3602
      Plectin; Plectin repeat

    10. XM_055512835.1 → XP_055368810.1  plectin a isoform X10

      UniProtKB/TrEMBL
      A0A9W2Y4G8
      Related
      ENSBSLP00000032755.2, ENSBSLT00000036249.3

    11. XM_055512836.1 → XP_055368811.1  plectin a isoform X10

      UniProtKB/TrEMBL
      A0A9W2Y4G8

    12. XM_029166529.3 → XP_029022362.1  plectin a isoform X19

      UniProtKB/TrEMBL
      A0A6P7NR39
      Conserved Domains (8) summary
      PTZ00121
      Location:1787 → 2656
      PTZ00121; MAEBL; Provisional
      smart00150
      Location:533 → 626
      SPEC; Spectrin repeats
      smart00250
      Location:2791 → 2825
      PLEC; Plectin repeat
      COG5069
      Location:35 → 264
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:628 → 818
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      pfam00681
      Location:4061 → 4100
      Plectin; Plectin repeat
      pfam15921
      Location:1013 → 1694
      CCDC158; Coiled-coil domain-containing protein 158
      cl27652
      Location:3410 → 3449
      Plectin; Plectin repeat

    13. XM_055512841.1 → XP_055368816.1  plectin a isoform X17

      UniProtKB/TrEMBL
      A0A9W2Y3W8
      Related
      ENSBSLP00000062852.2, ENSBSLT00000069570.2

    14. XM_029166531.3 → XP_029022364.1  plectin a isoform X25

      UniProtKB/TrEMBL
      A0A6P7NXY3
      Related
      ENSBSLP00000067762.1, ENSBSLT00000074753.2
      Conserved Domains (8) summary
      PTZ00121
      Location:1772 → 2641
      PTZ00121; MAEBL; Provisional
      smart00150
      Location:518 → 611
      SPEC; Spectrin repeats
      smart00250
      Location:2776 → 2810
      PLEC; Plectin repeat
      COG5069
      Location:20 → 249
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:613 → 803
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      pfam00681
      Location:4046 → 4085
      Plectin; Plectin repeat
      pfam15921
      Location:998 → 1679
      CCDC158; Coiled-coil domain-containing protein 158
      cl27652
      Location:3395 → 3434
      Plectin; Plectin repeat

    15. XM_055512843.1 → XP_055368818.1  plectin a isoform X22

      UniProtKB/TrEMBL
      A0A9W2Y462

    16. XM_055512844.1 → XP_055368819.1  plectin a isoform X23

      UniProtKB/TrEMBL
      A0A9W2Y4F7
      Related
      ENSBSLP00000032817.3, ENSBSLT00000036315.3

    17. XM_055512845.1 → XP_055368820.1  plectin a isoform X24

      UniProtKB/TrEMBL
      A0A9W2Y4H8

    18. XM_029166532.3 → XP_029022365.1  plectin a isoform X26

      UniProtKB/TrEMBL
      A0A6P7NWK1
      Related
      ENSBSLP00000032939.2, ENSBSLT00000036457.3
      Conserved Domains (8) summary
      PTZ00121
      Location:1770 → 2639
      PTZ00121; MAEBL; Provisional
      smart00150
      Location:516 → 609
      SPEC; Spectrin repeats
      smart00250
      Location:2774 → 2808
      PLEC; Plectin repeat
      COG5069
      Location:18 → 247
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:611 → 801
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      pfam00681
      Location:4044 → 4083
      Plectin; Plectin repeat
      pfam15921
      Location:996 → 1677
      CCDC158; Coiled-coil domain-containing protein 158
      cl27652
      Location:3393 → 3432
      Plectin; Plectin repeat

    19. XM_029166528.3 → XP_029022361.1  plectin a isoform X18

      UniProtKB/TrEMBL
      A0A6P7NR35
      Related
      ENSBSLP00000060038.2, ENSBSLT00000066678.2
      Conserved Domains (8) summary
      PTZ00121
      Location:1791 → 2660
      PTZ00121; MAEBL; Provisional
      smart00150
      Location:537 → 630
      SPEC; Spectrin repeats
      smart00250
      Location:2795 → 2829
      PLEC; Plectin repeat
      COG5069
      Location:34 → 268
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:632 → 822
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      pfam00681
      Location:4065 → 4104
      Plectin; Plectin repeat
      pfam15921
      Location:1017 → 1698
      CCDC158; Coiled-coil domain-containing protein 158
      cl27652
      Location:3414 → 3453
      Plectin; Plectin repeat

    20. XM_055512839.1 → XP_055368814.1  plectin a isoform X15

      UniProtKB/TrEMBL
      A0A9W2Y495

    21. XM_029166533.3 → XP_029022366.1  plectin a isoform X28

      UniProtKB/TrEMBL
      A0A6P7NR41
      Conserved Domains (8) summary
      PTZ00121
      Location:1764 → 2633
      PTZ00121; MAEBL; Provisional
      smart00150
      Location:525 → 618
      SPEC; Spectrin repeats
      smart00250
      Location:2768 → 2802
      PLEC; Plectin repeat
      COG5069
      Location:34 → 256
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:620 → 810
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      pfam00681
      Location:4038 → 4077
      Plectin; Plectin repeat
      pfam15921
      Location:990 → 1671
      CCDC158; Coiled-coil domain-containing protein 158
      cl27652
      Location:3387 → 3426
      Plectin; Plectin repeat

    22. XM_029166527.3 → XP_029022360.1  plectin a isoform X13

      UniProtKB/TrEMBL
      A0A6P7NWJ6
      Conserved Domains (8) summary
      PTZ00121
      Location:1799 → 2668
      PTZ00121; MAEBL; Provisional
      smart00150
      Location:553 → 646
      SPEC; Spectrin repeats
      smart00250
      Location:2803 → 2837
      PLEC; Plectin repeat
      COG5069
      Location:50 → 284
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:648 → 838
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      pfam00681
      Location:4073 → 4112
      Plectin; Plectin repeat
      pfam15921
      Location:1025 → 1706
      CCDC158; Coiled-coil domain-containing protein 158
      cl27652
      Location:3422 → 3461
      Plectin; Plectin repeat

    23. XM_029166534.3 → XP_029022367.1  plectin a isoform X12

      UniProtKB/TrEMBL
      A0A6P7NR46
      Related
      ENSBSLP00000032975.1, ENSBSLT00000036493.3
      Conserved Domains (8) summary
      PTZ00121
      Location:1807 → 2676
      PTZ00121; MAEBL; Provisional
      smart00150
      Location:553 → 646
      SPEC; Spectrin repeats
      smart00250
      Location:2811 → 2845
      PLEC; Plectin repeat
      COG5069
      Location:50 → 284
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:648 → 838
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      pfam00681
      Location:4081 → 4120
      Plectin; Plectin repeat
      pfam15921
      Location:1033 → 1714
      CCDC158; Coiled-coil domain-containing protein 158
      cl27652
      Location:3430 → 3469
      Plectin; Plectin repeat

    24. XM_055512837.1 → XP_055368812.1  plectin a isoform X11

      UniProtKB/TrEMBL
      A0A9W2Y4C6

    25. XM_029166530.3 → XP_029022363.1  plectin a isoform X21

      UniProtKB/TrEMBL
      A0A6P7NWL3
      Conserved Domains (8) summary
      PTZ00121
      Location:1780 → 2649
      PTZ00121; MAEBL; Provisional
      smart00150
      Location:541 → 634
      SPEC; Spectrin repeats
      smart00250
      Location:2784 → 2818
      PLEC; Plectin repeat
      COG5069
      Location:50 → 272
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00176
      Location:636 → 826
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
      pfam00681
      Location:4054 → 4093
      Plectin; Plectin repeat
      pfam15921
      Location:1006 → 1687
      CCDC158; Coiled-coil domain-containing protein 158
      cl27652
      Location:3403 → 3442
      Plectin; Plectin repeat

    26. XM_055512842.1 → XP_055368817.1  plectin a isoform X20

      UniProtKB/TrEMBL
      A0A9W2Y4C5

    27. XM_055512840.1 → XP_055368815.1  plectin a isoform X16

      UniProtKB/TrEMBL
      A0A9W2Y4N4

    28. XM_055512838.1 → XP_055368813.1  plectin a isoform X14

      UniProtKB/TrEMBL
      A0A9W2Y4B0

    29. XM_055512846.1 → XP_055368821.1  plectin a isoform X27

      UniProtKB/TrEMBL
      A0A9W2Y4D5
    Nucleotide Protein
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