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    SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 [ Apteryx rowi (Okarito brown kiwi) ]

    Gene ID: 112970482, updated on 15-Mar-2024

    Summary

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    Gene symbol
    SRGAP3
    Gene description
    SLIT-ROBO Rho GTPase activating protein 3
    See related
    Ensembl:ENSARWG00000015162
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Apteryx rowi
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Palaeognathae; Apterygiformes; Apterygidae; Apteryx
    Orthologs
    human mouse all
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    Genomic context

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    See SRGAP3 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    100 current aptRow1 (GCF_003343035.1) Unplaced Scaffold NW_020450529.1 (865487..945551)

    NW_020450529.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112970459 Neighboring gene interleukin 1 receptor associated kinase 2 Neighboring gene THUMP domain containing 3 Neighboring gene uncharacterized LOC112970483 Neighboring gene RAD18 E3 ubiquitin protein ligase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_020450529 Unplaced Scaffold Reference aptRow1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SLIT-ROBO Rho GTPase-activating protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Apteryx rowi Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference aptRow1

    Genomic

    1. NW_020450529.1 Reference aptRow1

      Range
      865487..945551
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_026074936.1 → XP_025930721.1  SLIT-ROBO Rho GTPase-activating protein 3 isoform X2

      Conserved Domains (3) summary
      cd11955
      Location:628 → 680
      SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
      cd04383
      Location:382 → 569
      RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
      cl12013
      Location:1 → 158
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    2. XM_026074935.1 → XP_025930720.1  SLIT-ROBO Rho GTPase-activating protein 3 isoform X1

      Related
      ENSARWP00000024446.1, ENSARWT00000027698.1
      Conserved Domains (3) summary
      cd11955
      Location:628 → 680
      SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
      cd04383
      Location:382 → 569
      RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
      cl12013
      Location:13 → 158
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    Nucleotide Protein
    Heading Accession and Version

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