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    usp8 ubiquitin specific peptidase 8 [ Oryzias melastigma (Indian medaka) ]

    Gene ID: 112160772, updated on 10-Jul-2024

    Summary

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    Gene symbol
    usp8
    Gene description
    ubiquitin specific peptidase 8
    See related
    EnsemblRapid:ENSOMEG00005004938
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryzias melastigma
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae; Oryzias
    Orthologs
    human zebrafish all
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    Genomic context

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    See usp8 in Genome Data Viewer
    Location:
    chromosome: LG3
    Exon count:
    22
    Annotation release Status Assembly LG Location
    101 current ASM292280v2 (GCF_002922805.2) LG3 NC_050514.1 (11168046..11180485, complement)
    100 previous assembly Om_v0.7.RACA (GCF_002922805.1) Unplaced Scaffold NW_020096099.1 (24403795..24416216)

    Linkage Group LG3 - NC_050514.1Genomic Context describing neighboring genes Neighboring gene LEO1 homolog, Paf1/RNA polymerase II complex component Neighboring gene mitogen-activated protein kinase 6 Neighboring gene putative ubiquitin carboxyl-terminal hydrolase 50 Neighboring gene very long-chain acyl-CoA synthetase Neighboring gene histidine decarboxylase Neighboring gene zgc:158482

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Tissue-specific transcriptome assemblies of the marine medaka Oryzias melastigma and comparative analysis with the freshwater medaka Oryzias latipes. Lai KP, et al. BMC Genomics, 2015 Feb 27. PMID 25765076, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Ras protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in endosome organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein K48-linked deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein K63-linked deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in dendritic spine IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extrinsic component of endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extrinsic component of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in midbody IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ubiquitin carboxyl-terminal hydrolase 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Oryzias melastigma Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM292280v2 Primary Assembly

    Genomic

    1. NC_050514.1 Reference ASM292280v2 Primary Assembly

      Range
      11168046..11180485 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024295560.2 → XP_024151328.1  ubiquitin carboxyl-terminal hydrolase 8

      UniProtKB/TrEMBL
      A0A3B3BX53, A0A3B3DD89
      Related
      ENSOMEP00005009553.1, ENSOMET00005010884.1
      Conserved Domains (4) summary
      smart00450
      Location:197 → 310
      RHOD; Rhodanese Homology Domain
      pfam00443
      Location:748 → 1077
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam08969
      Location:7 → 115
      USP8_dimer; USP8 dimerisation domain
      cl26464
      Location:320 → 472
      Atrophin-1; Atrophin-1 family

    2. XM_024295561.2 → XP_024151329.1  ubiquitin carboxyl-terminal hydrolase 8

      UniProtKB/TrEMBL
      A0A3B3BX53, A0A3B3DD89
      Related
      ENSOMEP00005009572.1, ENSOMET00005010903.1
      Conserved Domains (4) summary
      smart00450
      Location:197 → 310
      RHOD; Rhodanese Homology Domain
      pfam00443
      Location:748 → 1077
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam08969
      Location:7 → 115
      USP8_dimer; USP8 dimerisation domain
      cl26464
      Location:320 → 472
      Atrophin-1; Atrophin-1 family

    3. XM_024295563.2 → XP_024151331.1  ubiquitin carboxyl-terminal hydrolase 8

      UniProtKB/TrEMBL
      A0A3B3BX53, A0A3B3DD89
      Conserved Domains (4) summary
      smart00450
      Location:197 → 310
      RHOD; Rhodanese Homology Domain
      pfam00443
      Location:748 → 1077
      UCH; Ubiquitin carboxyl-terminal hydrolase
      pfam08969
      Location:7 → 115
      USP8_dimer; USP8 dimerisation domain
      cl26464
      Location:320 → 472
      Atrophin-1; Atrophin-1 family

    RNA

    1. XR_002921731.2 RNA Sequence

    2. XR_002921730.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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