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    TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 [ Neomonachus schauinslandi (Hawaiian monk seal) ]

    Gene ID: 110570457, updated on 15-Mar-2024

    Summary

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    Gene symbol
    TANC2
    Gene description
    tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
    See related
    EnsemblRapid:ENSNSCG00000014024
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Neomonachus schauinslandi
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae; Neomonachus
    Orthologs
    human mouse all
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    Genomic context

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    See TANC2 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    101 current ASM220157v2 (GCF_002201575.2) 15 NC_058417.1 (44520430..44817437)
    100 previous assembly ASM220157v1 (GCF_002201575.1) Unplaced Scaffold NW_018734265.1 (2039377..2339984)

    Chromosome 15 - NC_058417.1Genomic Context describing neighboring genes Neighboring gene membrane associated ring-CH-type finger 10 Neighboring gene uncharacterized LOC110570384 Neighboring gene transmembrane ascorbate-dependent reductase CYB561 Neighboring gene angiotensin I converting enzyme

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of dendritic spine morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in dendritic spine IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein TANC2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Neomonachus schauinslandi Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM220157v2

    Genomic

    1. NC_058417.1 Reference ASM220157v2

      Range
      44520430..44817437
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_044921763.1 → XP_044777698.1  protein TANC2 isoform X1

      UniProtKB/TrEMBL
      A0A8M1MXJ5
      Conserved Domains (7) summary
      PHA03095
      Location:930 → 1224
      PHA03095; ankyrin-like protein; Provisional
      PHA03307
      Location:1521 → 1674
      PHA03307; transcriptional regulator ICP4; Provisional
      COG0457
      Location:1324 → 1455
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      COG0666
      Location:1170 → 1296
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00006
      Location:1331 → 1356
      TPR; TPR repeat [structural motif]
      sd00045
      Location:1174 → 1204
      ANK; ANK repeat [structural motif]
      pfam03157
      Location:1559 → 1937
      Glutenin_hmw; High molecular weight glutenin subunit

    2. XM_021678492.2 → XP_021534167.1  protein TANC2 isoform X2

      UniProtKB/TrEMBL
      A0A2Y9G559
      Related
      ENSNSCP00000017715.1
      Conserved Domains (7) summary
      COG0457
      Location:1240 → 1371
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      cd00204
      Location:1094 → 1219
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00006
      Location:1247 → 1272
      TPR; TPR repeat [structural motif]
      sd00045
      Location:1100 → 1130
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:1038 → 1130
      Ank_2; Ankyrin repeats (3 copies)
      cl14876
      Location:395 → 539
      Zinc_peptidase_like; Zinc peptidases M18, M20, M28, and M42
      cl25764
      Location:1438 → 1621
      PAT1; Topoisomerase II-associated protein PAT1
    Nucleotide Protein
    Heading Accession and Version

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