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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001130060.2 → NP_001123532.1 cyclic AMP-dependent transcription factor ATF-7 isoform 3
See identical proteins and their annotated locations for NP_001123532.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) uses an alternate in-frame splice site in an internal exon, compared to variant 2, resulting in a shorter isoform (3, also known as ATFa1 or ATF-a delta), compared to isoform 2. There are no publicly available transcripts representing this variant; it is supported by data in PMIDs 1694576 and 8939888, and by alternative splicing annotation on accessions X52943.1 and X57197.1.
- Source sequence(s)
-
AC023509, BP279417, BP312300, BQ184780, DB047160, X52943
- UniProtKB/TrEMBL
-
B2R8U0
- Conserved Domains (3) summary
-
- cd12192
Location:47 → 84
- GCN4_cent; GCN4 central activation domain-like acidic activation domain
- cd14687
Location:313 → 373
- bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
- sd00019
Location:9 → 31
- ZF_C2H2; C2H2 Zn finger [structural motif]
-
NM_001206682.2 → NP_001193611.1 cyclic AMP-dependent transcription factor ATF-7 isoform 4
See identical proteins and their annotated locations for NP_001193611.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (4) differs in the 3' coding region and 3' UTR, compared to variant 2, resulting in an isoform (4) with a distinct and shorter C-terminus, compared to isoform 2. Variants 4, 5, and 13 all encode the same isoform (4).
- Source sequence(s)
-
AA679547, BC140006, DB047160
- Consensus CDS
-
CCDS58238.1
- UniProtKB/Swiss-Prot
-
P17544
- Related
- ENSP00000465192.1, ENST00000591397.1
- Conserved Domains (1) summary
-
- cd12192
Location:47 → 84
- GCN4_cent; GCN4 central activation domain-like acidic activation domain
-
NM_001206683.1 → NP_001193612.1 cyclic AMP-dependent transcription factor ATF-7 isoform 4
See identical proteins and their annotated locations for NP_001193612.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (5) differs in the 5' UTR, 3' coding region and 3' UTR, compared to variant 2, resulting in an isoform (4) with a distinct and shorter C-terminus, compared to isoform 2. Variants 4, 5, and 13 all encode the same isoform (4).
- Source sequence(s)
-
AA679547, AC023509, BC042363, DB490927
- Consensus CDS
-
CCDS58238.1
- UniProtKB/Swiss-Prot
-
P17544
- Related
- ENSP00000456858.1, ENST00000548118.6
- Conserved Domains (1) summary
-
- cd12192
Location:47 → 84
- GCN4_cent; GCN4 central activation domain-like acidic activation domain
-
NM_001366555.2 → NP_001353484.1 cyclic AMP-dependent transcription factor ATF-7 isoform 5
Status: VALIDATED
- Description
- Transcript Variant: This variant (7) encodes the longest isoform (5).
- Source sequence(s)
-
AC023509, AC073594
- Consensus CDS
-
CCDS44905.1
- UniProtKB/TrEMBL
-
B2R8U0
- Related
- ENSP00000449938.1, ENST00000548446.6
- Conserved Domains (3) summary
-
- cd12192
Location:47 → 84
- GCN4_cent; GCN4 central activation domain-like acidic activation domain
- cd14687
Location:345 → 405
- bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
- sd00019
Location:9 → 31
- ZF_C2H2; C2H2 Zn finger [structural motif]
-
NM_001366556.2 → NP_001353485.1 cyclic AMP-dependent transcription factor ATF-7 isoform 2
Status: VALIDATED
- Description
- Transcript Variant: This variant (8), as well as variants 2 and 9, encodes isoform 2.
- Source sequence(s)
-
AC023509, AC073594
- Consensus CDS
-
CCDS44906.1
- UniProtKB/Swiss-Prot
- A5D6Y4, B2RMP1, B4DQL4, P17544, Q13814, Q8IVR8, Q9UD83
- UniProtKB/TrEMBL
-
B2R8U0
- Related
- ENSP00000387406.3, ENST00000456903.8
- Conserved Domains (3) summary
-
- cd12192
Location:47 → 84
- GCN4_cent; GCN4 central activation domain-like acidic activation domain
- cd14687
Location:334 → 394
- bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
- sd00019
Location:9 → 31
- ZF_C2H2; C2H2 Zn finger [structural motif]
-
NM_001366558.2 → NP_001353487.1 cyclic AMP-dependent transcription factor ATF-7 isoform 2
Status: VALIDATED
- Description
- Transcript Variant: This variant (9), as well as variants 2 and 8, encodes isoform 2.
- Source sequence(s)
-
AC023509, AC073594
- Consensus CDS
-
CCDS44906.1
- UniProtKB/Swiss-Prot
- A5D6Y4, B2RMP1, B4DQL4, P17544, Q13814, Q8IVR8, Q9UD83
- UniProtKB/TrEMBL
-
B2R8U0
- Conserved Domains (3) summary
-
- cd12192
Location:47 → 84
- GCN4_cent; GCN4 central activation domain-like acidic activation domain
- cd14687
Location:334 → 394
- bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
- sd00019
Location:9 → 31
- ZF_C2H2; C2H2 Zn finger [structural motif]
-
NM_001366561.2 → NP_001353490.1 cyclic AMP-dependent transcription factor ATF-7 isoform 8
Status: VALIDATED
- Source sequence(s)
-
AC023509, AC073594
- UniProtKB/TrEMBL
-
B2R8U0
- Conserved Domains (1) summary
-
- cd14687
Location:279 → 339
- bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
-
NM_001366562.2 → NP_001353491.1 cyclic AMP-dependent transcription factor ATF-7 isoform 4
Status: VALIDATED
- Description
- Transcript Variant: This variant (13), as well as variants 4 and 5, encodes isoform 4.
- Source sequence(s)
-
AC023509, AC073594
- Consensus CDS
-
CCDS58238.1
- Conserved Domains (1) summary
-
- cd12192
Location:47 → 84
- GCN4_cent; GCN4 central activation domain-like acidic activation domain
-
NM_001366563.2 → NP_001353492.1 cyclic AMP-dependent transcription factor ATF-7 isoform 9
Status: VALIDATED
- Source sequence(s)
-
AC023509, AC073594
- Conserved Domains (1) summary
-
- cd12192
Location:18 → 54
- GCN4_cent; GCN4 central activation domain-like acidic activation domain
-
NM_006856.3 → NP_006847.1 cyclic AMP-dependent transcription factor ATF-7 isoform 2
See identical proteins and their annotated locations for NP_006847.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (2), as well as variants 8 and 9, encodes isoform 2 (also known as ATFa2).
- Source sequence(s)
-
AC023509, BP279417, BP312300, BQ184780, DB047160, X52943
- Consensus CDS
-
CCDS44906.1
- UniProtKB/Swiss-Prot
- A5D6Y4, B2RMP1, B4DQL4, P17544, Q13814, Q8IVR8, Q9UD83
- UniProtKB/TrEMBL
-
B2R8U0
- Related
- ENSP00000399465.1, ENST00000420353.7
- Conserved Domains (3) summary
-
- cd12192
Location:47 → 84
- GCN4_cent; GCN4 central activation domain-like acidic activation domain
- cd14687
Location:334 → 394
- bZIP_ATF2; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-2 (ATF-2) and similar proteins: a DNA-binding and dimerization domain
- sd00019
Location:9 → 31
- ZF_C2H2; C2H2 Zn finger [structural motif]
RNA
-
NR_073163.2 RNA Sequence
Status: VALIDATED
- Description
- Transcript Variant: This variant (6) use an alternate splice site in an internal exon and has an alternate 3' structure, compared to variant 2. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 2, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC073594, AK298853
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000012.12 Reference GRCh38.p14 Primary Assembly
- Range
-
53507856..53626382 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060936.1 Alternate T2T-CHM13v2.0
- Range
-
53473861..53592424 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_001130059.1: Suppressed sequence
- Description
- NM_001130059.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.