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    gch2 GTP cyclohydrolase 2 [ Scleropages formosus (Asian bonytongue) ]

    Gene ID: 108931478, updated on 14-Mar-2024

    Summary

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    Gene symbol
    gch2
    Gene description
    GTP cyclohydrolase 2
    See related
    Ensembl:ENSSFOG00015008466
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Scleropages formosus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala; Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages
    Orthologs
    zebrafish all
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    Genomic context

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    See gch2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    101 current fSclFor1.1 (GCF_900964775.1) 3 NC_041808.1 (4674887..4679775)
    100 previous assembly ASM162426v1 (GCF_001624265.1) Unplaced Scaffold NW_017371512.1 (68019..72988)

    Chromosome 3 - NC_041808.1Genomic Context describing neighboring genes Neighboring gene tumor-associated calcium signal transducer 2-like Neighboring gene calmodulin 2b, (phosphorylase kinase, delta) Neighboring gene cysteine-rich PDZ-binding protein Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class F Neighboring gene ras homolog family member Q

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTP cyclohydrolase I activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in tetrahydrobiopterin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tetrahydrofolate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GTP cyclohydrolase 1-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Scleropages formosus Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference fSclFor1.1 Primary Assembly

    Genomic

    1. NC_041808.1 Reference fSclFor1.1 Primary Assembly

      Range
      4674887..4679775
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_029250525.1 → XP_029106358.1  GTP cyclohydrolase 1-like

      UniProtKB/TrEMBL
      A0A0P7X2F7, A0A8C9V0X2
      Related
      ENSSFOP00015013186.2, ENSSFOT00015013351.2
      Conserved Domains (1) summary
      cd00642
      Location:48 → 231
      GTP_cyclohydro1; GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate. The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria. In ...
    Nucleotide Protein
    Heading Accession and Version

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