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    LOC108897292 phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [ Lates calcarifer (barramundi perch) ]

    Gene ID: 108897292, updated on 10-Apr-2024

    Summary

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    Gene symbol
    LOC108897292
    Gene description
    phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
    See related
    EnsemblRapid:ENSLCAG00010007107
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Lates calcarifer
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Carangaria; Carangaria incertae sedis; Centropomidae; Lates
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    Genomic context

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    See LOC108897292 in Genome Data Viewer
    Location:
    chromosome: LG16_LG22
    Exon count:
    10
    Annotation release Status Assembly LG Location
    RS_2023_02 current TLL_Latcal_v3 (GCF_001640805.2) LG16_LG22 NC_066848.1 (10606627..10617592)
    100 previous assembly ASM164080v1 (GCF_001640805.1) Unplaced Scaffold NW_017365859.1 (237653..248460)

    Linkage Group LG16_LG22 - NC_066848.1Genomic Context describing neighboring genes Neighboring gene multiple inositol polyphosphate phosphatase 1 Neighboring gene bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 Neighboring gene cholesterol 25-hydroxylase-like protein Neighboring gene Fas cell surface death receptor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Immune transcriptome reveals the mincle C-type lectin receptor acts as a partial replacement for TLR4 in lipopolysaccharide-mediated inflammatory response in barramundi (Lates calcarifer). Zoccola E, et al. Mol Immunol, 2017 Mar. PMID 28095348
    2. Primary analysis of repeat elements of the Asian seabass (Lates calcarifer) transcriptome and genome. Kuznetsova IS, et al. Front Genet, 2014. PMID 25120555, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell motility IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of cell population proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_001640805.2-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference TLL_Latcal_v3 Primary Assembly

    Genomic

    1. NC_066848.1 Reference TLL_Latcal_v3 Primary Assembly

      Range
      10606627..10617592
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018696847.2 → XP_018552363.1  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1

      UniProtKB/TrEMBL
      A0A4W6CR97
      Related
      ENSLCAP00010015009.1, ENSLCAT00010015326.2

    2. XM_018696849.2 → XP_018552365.1  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X2

      UniProtKB/TrEMBL
      A0A4W6CRA3
      Related
      ENSLCAP00010015014.1, ENSLCAT00010015331.2
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Molecular Biology Databases